Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.45 |
| ▸ | NOX4 | Q9NPH5 | 3/20 | 0.40 |
| ▸ | DCK | P27707 | 4/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.39 |
| ▸ | PDE5A | O76074 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 3/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12932953 | 0.86 | HTR6 (0.43) | DCKHTR6 | |
| SCHEMBL12900467 | 0.83 | DCK (0.43) | DCKALDH1A1PTGS2 | |
| SCHEMBL12900477 | 0.83 | MEN1 (0.45) | NOD1DCKHTR6ALDH1A1 | |
| SCHEMBL1271033 | 0.83 | ALDH1A1 (0.48) | NOD1DCKHTR6ALDH1A1 | |
| SCHEMBL1270873 | 0.83 | DCK (0.49) | NOD1DCKHTR6ALDH1A1 | |
| SCHEMBL12900482 | 0.80 | HTR6 (0.44) | NOD1DCKHTR6ALDH1A1 | |
| SCHEMBL12900473 | 0.80 | DCK (0.44) | DCKHTR6 | |
| SCHEMBL12900475 | 0.77 | NOD1 (0.44) | NOD1DCKHTR6EIF2AK3 | |
| SCHEMBL12900476 | 0.71 | MET (0.40) | DCK | |
| Benzene SCHEMBL28349605 | 0.69 | DCK (0.41) | DCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9862686-B2 | N1-sulfonyl-5-fluoropyrimidinone derivatives | ADAMA MAKHTESHIM LTD. (IL) | 2018-01-09 | — | — | US | disclosed |
| US-20150191436-A1 | N1-SULFONYL-5-FLUOROPYRIMIDINONE DERIVATIVES | ADAMA MAKHTESHIM LTD. (IL) | 2015-07-09 | — | — | US | disclosed |
| US-20150191436-A1 | N1-SULFONYL-5-FLUOROPYRIMIDINONE DERIVATIVES | ADAMA MAKHTESHIM LTD. (IL) | 2015-07-09 | — | — | US | disclosed |
| US-9006259-B2 | N1-sulfonyl-5-fluoropyrimidinone derivatives | DOW AGROSCIENCES LLC (US) | 2015-04-14 | — | — | US | disclosed |
| US-9006259-B2 | N1-sulfonyl-5-fluoropyrimidinone derivatives | DOW AGROSCIENCES LLC (US) | 2015-04-14 | — | — | US | disclosed |
| EP-2462134-B1 | N1-SULFONYL-5-FLUOROPYRIMIDINONE DERIVATIVES | DOW AGROSCIENCES LLC (US) | 2014-05-07 | — | — | EP | disclosed |
| US-20110034493-A1 | N1-SULFONYL-5-FLUOROPYRIMIDINONE DERIVATIVES | DOW AGROSCIENCES LLC (US) | 2011-02-10 | — | — | US | disclosed |
| WO-2011017547-A1 | N1-SULFONYL-5-FLUOROPYRIMIDINONE DERIVATIVES | DOW AGROSCIENCES LLC (US) | 2011-02-10 | — | — | WO | disclosed |
| US-20110034493-A1 | N1-SULFONYL-5-FLUOROPYRIMIDINONE DERIVATIVES | DOW AGROSCIENCES LLC (US) | 2011-02-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150191436-A1 | N1-SULFONYL-5-FLUOROPYRIMIDINONE DERIVATIVES | DDT, SULT1E1, CYP1A1 | NOD1 1986/4885NOX4 240/4885DCK 3154/4885 |
| US-20110034493-A1 | N1-SULFONYL-5-FLUOROPYRIMIDINONE DERIVATIVES | DDT, SULT1E1, CYP1A1 | NOD1 1986/4885NOX4 240/4885DCK 3154/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.