Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 7/20 | 0.38 |
| ▸ | MMP3 | P08254 | 6/20 | 0.38 |
| ▸ | MMP1 | P03956 | 6/20 | 0.38 |
| ▸ | MMP13 | P45452 | 6/20 | 0.38 |
| ▸ | MMP7 | P09237 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MMP8 | P22894 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP12 | P39900 | 1/20 | 0.34 |
| ▸ | MMP14 | P50281 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14878470 | 0.92 | CASP1 (0.40) | CASP1MMP9MMP3MMP1MMP13 | |
| SCHEMBL12905430 | 0.92 | ALDH1A1 (0.35) | MMP9MMP3MMP1MMP13MMP7 | |
| SCHEMBL12905433 | 0.91 | LMNA (0.39) | MMP9MMP3MMP1MMP13MMP7 | |
| SCHEMBL778857 | 0.90 | MMP1 (0.49) | MMP9MMP3MMP1MMP13MMP7 | |
| SCHEMBL12905395 | 0.87 | MMP1 (0.48) | CASP1MMP9MMP3MMP1MMP13 | |
| SCHEMBL12905412 | 0.85 | MMP9 (0.46) | MMP9MMP3MMP1MMP13MMP7 | |
| SCHEMBL12905480 | 0.85 | ALDH1A1 (0.37) | MMP9MMP3MMP1MMP13MMP7 | |
| SCHEMBL14878442 | 0.84 | MMP1 (0.36) | MMP9MMP3MMP1MMP13MMP7 | |
| SCHEMBL12905401 | 0.84 | MMP9 (0.38) | CASP1MMP9MMP3MMP1MMP13 | |
| SCHEMBL12905432 | 0.83 | ALDH1A1 (0.39) | MMP9MMP3MMP1MMP13MMP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8426415-B2 | Human ADAM-10 inhibitors | SYMPHONY EVOLUTION, INC. (US) | 2013-04-23 | — | — | US | disclosed |
| US-20110003812-A1 | Human Adam-10 Inhibitors | SYMPHONY EVOLUTION, INC. (US) | 2011-01-06 | — | — | US | disclosed |
| US-20110003812-A1 | Human Adam-10 Inhibitors | SYMPHONY EVOLUTION, INC. (US) | 2011-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110003812-A1 | Human Adam-10 Inhibitors | ADAM10, MMP20, ADAM9 | CASP1 176/4885MMP9 12/4885MMP3 30/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.