Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 2/20 | 0.44 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 7/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | GFER | P55789 | 4/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CASP6 | P55212 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | GAA | P10253 | 4/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1377738 | 0.69 | KDM1A (0.46) | DDB1CRBNMAPTALDH1A1GFER | |
| SCHEMBL18631240 | 0.69 | CACNA1B (0.43) | MAPTALDH1A1GFERHTTLMNA | |
| SCHEMBL22055778 | 0.68 | PIK3CD (0.46) | DDB1CRBNMAPTALDH1A1TDP1 | |
| SCHEMBL76558 | 0.67 | F10 (0.58) | DDB1CRBN | |
| SCHEMBL15525159 | 0.67 | DGAT1 (0.45) | DDB1CRBNMAPTALDH1A1GFER | |
| SCHEMBL13003406 | 0.67 | DDB1 (0.40) | DDB1CRBNMAPTALDH1A1GFER | |
| SCHEMBL85673 | 0.66 | ALDH1A1 (0.50) | DDB1CRBNMAPTALDH1A1GFER | |
| SCHEMBL13003396 | 0.65 | — | — | |
| SCHEMBL13003415 | 0.65 | RAB9A (0.40) | DDB1CRBNMAPTALDH1A1GFER | |
| SCHEMBL15319324 | 0.64 | DDB1 (0.45) | DDB1CRBNMAPTALDH1A1GFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7847096-B2 | 4-aminophenylmorpholinone derivatives and their preparation | SALTIGO GMBH (DE) | 2010-12-07 | — | — | US | disclosed |
| US-7847096-B2 | 4-aminophenylmorpholinone derivatives and their preparation | SALTIGO GMBH (DE) | 2010-12-07 | — | — | US | disclosed |
| EP-1802311-B1 | 4-AMINOPHENYL MORPHOLINONE DERIVATIVES FOR THE TREATMENT OF HEPATITIS C | SALTIGO GMBH (DE) | 2009-03-18 | — | — | EP | disclosed |
| US-20090018126-A1 | 4-Aminophenylmorpholinone Derivatives and Their Preparation | SALTIGO GMBH (DE) | 2009-01-15 | — | — | US | disclosed |
| US-20090018126-A1 | 4-Aminophenylmorpholinone Derivatives and Their Preparation | SALTIGO GMBH (DE) | 2009-01-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090018126-A1 | 4-Aminophenylmorpholinone Derivatives and Their Preparation | HTR3C, ADRA2C, OPRM1 | DDB1 2837/4885CRBN 921/4885MAPT 553/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.