SCHEMBL13019481

SCHEMBL13019481

[C-]#[N+]c1ccc(-c2ccc(-c3ccc(-c4ccncc4)cc3)cc2)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.55
LMNA P02545 1/20 0.55
NOTUM Q6P988 1/20 0.46
KIF11 P52732 2/20 0.44
SMN1; SMN2 Q16637 1/20 0.43
HDAC1 Q13547 1/20 0.42
HDAC6 Q9UBN7 1/20 0.42
QDPR P09417 1/20 0.41
PABPC1 P11940 1/20 0.38
APOBEC3A P31941 1/20 0.38
EIF4H Q15056 1/20 0.38
APOBEC3G Q9HC16 1/20 0.38
CYP17A1 P05093 2/20 0.37
CYP11B1 P15538 2/20 0.37
CYP21A2 P08686 1/20 0.37
CYP3A4 P08684 3/20 0.36
CYP2D6 P10635 2/20 0.36
AAK1 Q2M2I8 1/20 0.36
DDAH1 O94760 1/20 0.36
NOS1 P29475 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3413995 0.84
SCHEMBL10000032 0.78 MAPT (0.92) MAPTLMNANOTUMKIF11SMN1; SMN2
SCHEMBL135626 0.78 MAPT (0.92) MAPTLMNANOTUMKIF11SMN1; SMN2
SCHEMBL9728 0.74 MAPT (1.00) MAPTLMNANOTUMKIF11SMN1; SMN2
SCHEMBL92056 0.74 ALDH1A1 (0.50) MAPTNOTUMKIF11SMN1; SMN2CYP3A4
SCHEMBL13019607 0.72 ALDH1A1 (0.48) MAPTSMN1; SMN2HDAC1
SCHEMBL10295281 0.72 ESR1 (0.58) MAPTLMNAKIF11SMN1; SMN2CYP3A4
SCHEMBL12692354 0.72 ACHE (0.42) MAPTLMNAKIF11CYP3A4CYP2D6
SCHEMBL13410607 0.72 ACHE (0.42) MAPTLMNAKIF11CYP3A4CYP2D6
SCHEMBL13019483 0.71 KIF11 (0.54) KIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9711176-B2 Multilayer optical information recording disk and method for manufacturing same FUJIFILM CORPORATION (JP) 2017-07-18 US disclosed
US-9514779-B2 Method for manufacturing multilayer structure sheet, and optical information recording medium FUJIFILM CORPORATION (JP) 2016-12-06 US disclosed
US-20150364153-A1 METHOD FOR MANUFACTURING OPTICAL INFORMATION RECORDING MEDIUM FUJIFILM CORPORATION (JP) 2015-12-17 US disclosed
US-20150318013-A1 MULTILAYER OPTICAL INFORMATION RECORDING DISK AND METHOD FOR MANUFACTURING SAME FUJIFILM CORPORATION (JP) 2015-11-05 US disclosed
US-8980396-B2 Optical information recording medium FUJIFILM CORPORATION (JP) 2015-03-17 US disclosed
US-8953427-B2 Optical information recording medium FUJIFILM CORPORATION (JP) 2015-02-10 US disclosed
US-20140193601-A1 METHOD FOR MANUFACTURING MULTILAYER STRUCTURE SHEET, AND OPTICAL INFORMATION RECORDING MEDIUM FUJIFILM CORPORATION (JP) 2014-07-10 US disclosed
US-20140153375-A1 OPTICAL INFORMATION RECORDING MEDIUM, METHOD FOR MANUFACTURING SAME AND RECORDING METHOD FOR OPTICAL INFORMATION RECORDING MEDIUM FUJIFILM CORPORATION (JP) 2014-06-05 US disclosed
US-8670296-B2 Optical information recording medium and optical information recording method FUJIFILM CORPORATION (JP) 2014-03-11 US disclosed
US-20140023816-A1 OPTICAL INFORMATION RECORDING MEDIUM FUJIFILM CORPORATION (JP) 2014-01-23 US disclosed
US-20130229901-A1 OPTICAL INFORMATION RECORDING MEDIUM FUJIFILM CORPORATION (JP) 2013-09-05 US disclosed
US-8526291-B2 Optical information recording medium FUJIFILM CORPORATION (JP) 2013-09-03 US disclosed
US-20130128710-A1 OPTICAL INFORMATION RECORDING MEDIUM FUJIFILM CORPORATION (JP) 2013-05-23 US disclosed
US-20130100791-A1 OPTICAL INFORMATION RECORDING MEDIUM AND OPTICAL INFORMATION RECORDING METHOD FUJIFILM CORPORATION (JP) 2013-04-25 US disclosed
US-20100330496-A1 SIMULTANEOUS TWO-PHOTON ABSORPTION RECORDING-REPRODUCTION METHOD, AND SIMULTANEOUS TWO-PHOTON ABSORPTION RECORDING MATERIAL FOR USE THEREIN FUJIFILM CORPORATION (JP) 2010-12-30 US disclosed
US-20100078607-A1 NON-RESONANT TWO-PHOTON ABSORPTION RECORDING MATERIAL AND NON-RESONANT TWO-PHOTON ABSORPTION COMPOUND FUJIFILM CORPORATION (JP) 2010-04-01 US disclosed
US-20090246443-A1 SIMULTANEOUS TWO-PHOTON ABSORPTION THREE-DIMENSIONAL OPTICAL RECORDING MEDIUM AND SIMULTANEOUS TWO-PHOTON THREE-DIMENSIONAL OPTICAL RECORDING METHOD FUJIFILM CORPORATION (JP) 2009-10-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100078607-A1 NON-RESONANT TWO-PHOTON ABSORPTION RECORDING MATERIAL AND NON-RESONANT TWO-PHOTON ABSORPTION COMPOUND SIGMAR1, SFN, CRY2 MAPT 4332/4885LMNA 1647/4885NOTUM 1257/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.