SCHEMBL132967

SCHEMBL132967

Cc1cc(C)cc(-c2cccc(-c3nc(C(=O)c4nc(-c5cccc(-c6cc(C)cc(C)c6)c5)nc(-c5cccc(-c6cc(C)cc(C)c6)c5)n4)nc(-c4cccc(-c5cc(C)cc(C)c5)c4)n3)c2)c1

nearest known ligand 0.45

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 1/20 0.44
DHODH Q02127 3/20 0.43
RXRA P19793 1/20 0.42
RXRB P28702 1/20 0.42
RORC P51449 1/20 0.40
MAPK14 Q16539 1/20 0.40
KMO O15229 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP2C9 P11712 1/20 0.39
SYK P43405 1/20 0.39
TP53 P04637 1/20 0.38
MAPT P10636 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
CNR1 P21554 1/20 0.37
CNR2 P34972 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21397903 0.94 RXRA (0.45) RAB9ADHODHRXRARXRBRORC
SCHEMBL132058 0.84 RXRA (0.42) RAB9ARXRARXRBKMOCNR2
SCHEMBL133749 0.83 KMO (0.53) DHODHKMOL3MBTL1
SCHEMBL12551824 0.83 KMO (0.53) DHODHKMOL3MBTL1
SCHEMBL4546942 0.81 L3MBTL1 (0.55) RAB9ADHODHMAPTL3MBTL1
SCHEMBL12551442 0.81 ALDH1A1 (0.42) RAB9ADHODHCYP1A2CYP2C9MAPT
SCHEMBL134233 0.79 DHODH (0.54) DHODHRXRARXRBKMOSYK
SCHEMBL10039117 0.79 KMO (0.53) DHODHRXRARXRBKMOMAPT
SCHEMBL12551667 0.79 KMO (0.53) DHODHRXRARXRBKMOMAPT
SCHEMBL12551833 0.79 KMO (0.53) DHODHRXRARXRBKMOMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11535640-B2 Metal complexes MERCK PATENT GMBH (DE) 2022-12-27 US disclosed
EP-2984152-B2 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2022-01-05 EP disclosed
US-11145828-B2 Metal complexes MERCK PATENT GMBH (DE) 2021-10-12 US disclosed
US-11024815-B2 Metal complexes MERCK PATENT GMBH (DE) 2021-06-01 US disclosed
EP-3658564-B1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2021-05-19 EP disclosed
US-10889604-B2 Binuclear and trinuclear metal complexes composed of two inter-linked tripodal hexadentate ligands for use in electroluminescent devices MERCK PATENT GMBH 2021-01-12 US disclosed
EP-3117470-B1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2020-12-23 EP disclosed
US-20200207794-A1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2020-07-02 US disclosed
EP-2627730-B1 FORMULATIONS FOR ORGANIC ELECTROLUMINESCENCE DEVICES MERCK PATENT GMBH (DE) 2020-05-06 EP disclosed
US-10636990-B2 Organic electroluminescence device MERCK PATENT GMBH (DE) 2020-04-28 US disclosed
US-20120037896-A1 ORGANIC ELECTROLUMINESCENCE DEVICE MERCK PATENT GMBH (DE) 2012-02-16 US disclosed
US-20110284831-A1 ORGANIC ELECTROLUMINESCENCE DEVICE MERCK PATENT GMBH (DE) 2011-11-24 US disclosed
US-20110284831-A1 ORGANIC ELECTROLUMINESCENCE DEVICE MERCK PATENT GMBH (DE) 2011-11-24 US disclosed
WO-2011141109-A1 ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2011-11-17 WO disclosed
US-20110140043-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICE MERCK PATENT GMBH (DE) 2011-06-16 US disclosed
US-20110140043-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICE MERCK PATENT GMBH (DE) 2011-06-16 US disclosed
US-20110108818-A1 ORGANIC ELECTROLUMINESCENCE DEVICE MERCK PATENT GMBH (DE) 2011-05-12 US disclosed
US-20110108818-A1 ORGANIC ELECTROLUMINESCENCE DEVICE MERCK PATENT GMBH (DE) 2011-05-12 US disclosed
WO-2010115498-A1 ORGANIC ELECTROLUMINESCENCE DEVICE MERCK PATENT GMBH (DE) 2010-10-14 WO disclosed
WO-2010102706-A1 ORGANIC ELECTROLUMINESCENCE DEVICE MERCK PATENT GMBH (DE) 2010-09-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11145828-B2 Metal complexes AP1M1, AP2M1, AP3M1 RAB9A 2280/4885DHODH 4150/4885RXRA 3747/4885
US-11024815-B2 Metal complexes EXOC4, EXOC3, TIMCC RAB9A 2171/4885DHODH 3418/4885RXRA 2518/4885
US-20110140043-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICE L1CAM, SLCO4C1, GJA1 RAB9A 2620/4885DHODH 3617/4885RXRA 3079/4885
US-10889604-B2 Binuclear and trinuclear metal complexes composed of two inter-linked tripodal hexadentate ligands for use in electroluminescent devices PARN, PUF60, PARG RAB9A 3136/4885DHODH 4174/4885RXRA 1578/4885
US-20200207794-A1 METAL COMPLEXES IMMT, MCU, SOD1 RAB9A 2000/4885DHODH 3251/4885RXRA 3459/4885
US-11535640-B2 Metal complexes IMMT, MCU, SOD1 RAB9A 2000/4885DHODH 3251/4885RXRA 3459/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.