SCHEMBL13299574

SCHEMBL13299574

Cc1cccc(-c2cc(C)c(C)c(C)n2)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 4/20 0.49
KDM4E B2RXH2 3/20 0.49
ALDH1A1 P00352 2/20 0.49
MEN1 O00255 1/20 0.49
POLB P06746 1/20 0.49
MAPT P10636 1/20 0.49
PKM P14618 1/20 0.49
KMT2A Q03164 1/20 0.49
XDH P47989 1/20 0.47
IDO1 P14902 1/20 0.46
METAP2 P50579 1/20 0.46
NPC1 O15118 2/20 0.44
CTSS P25774 1/20 0.43
CTSK P43235 1/20 0.43
KMO O15229 2/20 0.43
BCHE P06276 1/20 0.43
ACHE P22303 1/20 0.43
NFKB1 P19838 1/20 0.43
NFKB2 Q00653 1/20 0.43
RELA Q04206 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13299548 0.82 ALDH1A1 (0.69) RAB9AKDM4EALDH1A1MEN1POLB
SCHEMBL13299577 0.79 KMO (0.47) RAB9AKDM4EALDH1A1XDHIDO1
SCHEMBL12264968 0.78 RAB9A (0.54) RAB9AKDM4EALDH1A1XDHIDO1
SCHEMBL12264969 0.76 XDH (0.53) RAB9AKDM4EXDHIDO1METAP2
SCHEMBL4546867 0.76 XDH (0.53) RAB9AKDM4EMEN1KMT2AXDH
SCHEMBL4546906 0.76 RAB9A (0.66) RAB9AKDM4EALDH1A1MEN1MAPT
SCHEMBL12973115 0.76 RAB9A (0.53) RAB9AKDM4EALDH1A1XDHIDO1
SCHEMBL3629467 0.76 IDO1 (0.55) RAB9AKDM4EMEN1KMT2AXDH
SCHEMBL10604269 0.76 IDO1 (0.51) RAB9AKDM4EXDHIDO1METAP2
SCHEMBL18876337 0.75 CYP19A1 (0.54) RAB9AKDM4EALDH1A1MEN1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11697653-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-07-11 US disclosed
US-11639363-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-05-02 US disclosed
US-8367223-B2 Heteroleptic phosphorescent emitters UNIVERSAL DISPLAY CORPORATION (US) 2013-02-05 US disclosed
US-8367223-B2 Heteroleptic phosphorescent emitters UNIVERSAL DISPLAY CORPORATION (US) 2013-02-05 US disclosed
US-20100141127-A1 PHOSPHORESCENT EMITTERS UNIVERSAL DISPLAY CORPORATION (US) 2010-06-10 US disclosed
US-20100141127-A1 PHOSPHORESCENT EMITTERS UNIVERSAL DISPLAY CORPORATION (US) 2010-06-10 US disclosed
WO-2010056669-A1 PHOSPHORESCENT EMITTERS UNIVERSAL DISPLAY CORPORATION (US) 2010-05-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11697653-B2 Organic electroluminescent materials and devices L1CAM, SOD1, EPCAM RAB9A 2611/4885KDM4E 4003/4885ALDH1A1 380/4885
US-20100141127-A1 PHOSPHORESCENT EMITTERS PAICS, TYMP, NUDT1 RAB9A 2958/4885KDM4E 2674/4885ALDH1A1 695/4885
US-11639363-B2 Organic electroluminescent materials and devices LEF1, L1CAM, SSB RAB9A 925/4885KDM4E 2512/4885ALDH1A1 560/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.