SCHEMBL13299577

SCHEMBL13299577

Cc1cccc(-c2ccc(C)c(C)n2)c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMO O15229 2/20 0.47
IDO1 P14902 1/20 0.47
METAP2 P50579 1/20 0.47
RAB9A P51151 3/20 0.46
NPC1 O15118 2/20 0.45
KDM4E B2RXH2 1/20 0.45
XDH P47989 1/20 0.45
ACHE P22303 2/20 0.44
BCHE P06276 1/20 0.44
ALDH1A1 P00352 1/20 0.44
NFKB1 P19838 1/20 0.44
NFKB2 Q00653 1/20 0.44
RELA Q04206 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
ENPP3 O14638 1/20 0.44
ATP4A P20648 2/20 0.42
ATP4B P51164 2/20 0.42
KDM1A O60341 1/20 0.42
CTSS P25774 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12264970 0.83 RAB9A (0.49) KMOIDO1METAP2RAB9ANPC1
SCHEMBL13036054 0.81 IDO1 (0.49) KMOIDO1METAP2RAB9ANPC1
SCHEMBL20632252 0.81 MAP4K4 (0.51) KMOIDO1RAB9ANPC1
SCHEMBL3629467 0.81 IDO1 (0.55) KMOIDO1METAP2RAB9ANPC1
SCHEMBL20631587 0.80 KIF11 (0.50) KDM4EALDH1A1KDM1ACTSSCTSK
SCHEMBL4401764 0.79 IDO1 (0.53) KMOIDO1METAP2RAB9ANPC1
SCHEMBL13299549 0.79 ALDH1A1 (0.58) RAB9ANPC1KDM4EALDH1A1SMN1; SMN2
SCHEMBL13299574 0.79 RAB9A (0.49) KMOIDO1METAP2RAB9ANPC1
SCHEMBL15460382 0.79 NPC1 (0.47) KMOIDO1METAP2RAB9ANPC1
SCHEMBL20632693 0.79 IDO1 (0.50) IDO1RAB9AALDH1A1SMN1; SMN2KDM1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240074301-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-02-29 US disclosed
US-11839141-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-12-05 US disclosed
US-11827651-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-11-28 US disclosed
US-11814403-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-11-14 US disclosed
US-20230345811-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-26 US disclosed
US-20230345812-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-26 US disclosed
US-20230337522-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-19 US disclosed
US-20230337523-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-19 US disclosed
US-20230322829-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-12 US disclosed
US-20230309396-A1 Host Materials for Electroluminscent Devices UNIVERSAL DISPLAY CORPORATION 2023-09-28 US disclosed
US-20210380617-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-12-09 US disclosed
US-20210376261-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-12-02 US disclosed
US-20210347797-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-11-11 US disclosed
US-20210284672-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-09-16 US disclosed
EP-2997029-B1 SUBSTITUTED BRIDGED UREA ANALOGS AS SIRTUIN MODULATORS GLAXOSMITHKLINE LLC (US) 2019-01-09 EP disclosed
US-8367223-B2 Heteroleptic phosphorescent emitters UNIVERSAL DISPLAY CORPORATION (US) 2013-02-05 US disclosed
US-8367223-B2 Heteroleptic phosphorescent emitters UNIVERSAL DISPLAY CORPORATION (US) 2013-02-05 US disclosed
US-20100141127-A1 PHOSPHORESCENT EMITTERS UNIVERSAL DISPLAY CORPORATION (US) 2010-06-10 US disclosed
US-20100141127-A1 PHOSPHORESCENT EMITTERS UNIVERSAL DISPLAY CORPORATION (US) 2010-06-10 US disclosed
WO-2010056669-A1 PHOSPHORESCENT EMITTERS UNIVERSAL DISPLAY CORPORATION (US) 2010-05-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (15 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230309396-A1 Host Materials for Electroluminscent Devices CRHR1, CRHR2, CRH KMO 3669/4885IDO1 3491/4885METAP2 4692/4885
US-20100141127-A1 PHOSPHORESCENT EMITTERS PAICS, TYMP, NUDT1 KMO 4064/4885IDO1 1932/4885METAP2 1019/4885
US-20230337522-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES L1CAM, EML4, LBR KMO 4151/4885IDO1 2660/4885METAP2 2882/4885
US-20230345812-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OPRD1, OCIAD2 KMO 3303/4885IDO1 2412/4885METAP2 4831/4885
US-20210284672-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES PDCD1, TEC, PDCD4 KMO 1576/4885IDO1 38/4885METAP2 3350/4885
US-11814403-B2 Organic electroluminescent materials and devices PDCD1, TEC, PDCD4 KMO 1753/4885IDO1 39/4885METAP2 3448/4885
US-20230337523-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LBR, OCIAD1, OCIAD2 KMO 4095/4885IDO1 2894/4885METAP2 4724/4885
US-11839141-B2 Organic electroluminescent materials and devices OSBP, OCIAD1, OCIAD2 KMO 2716/4885IDO1 1130/4885METAP2 3731/4885
US-20240074301-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES ICOSLG, OCIAD2, OSBP KMO 2569/4885IDO1 1353/4885METAP2 4318/4885
US-20210376261-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, TPO KMO 2467/4885IDO1 962/4885METAP2 2497/4885
US-20210347797-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, TPO KMO 2467/4885IDO1 962/4885METAP2 2497/4885
US-20230322829-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, ICOSLG KMO 2420/4885IDO1 201/4885METAP2 4612/4885
US-11827651-B2 Organic electroluminescent materials and devices SSB, L1CAM, LEF1 KMO 4390/4885IDO1 3778/4885METAP2 3798/4885
US-20210380617-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES SOD1, CRKL, ROS1 KMO 1894/4885IDO1 3387/4885METAP2 4123/4885
US-20230345811-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OPRD1, L1CAM, OPRM1 KMO 3713/4885IDO1 1719/4885METAP2 3011/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.