Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
| ▸ | ABCC9 | O60706 | 2/20 | 0.39 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.37 |
| ▸ | ICMT | O60725 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.36 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5516545 | 0.83 | ALDH1A1 (0.44) | LOXL2GAAABCG2CYP2A6ALDH1A1 | |
| SCHEMBL5712390 | 0.81 | PRSS1 (0.46) | LOXL2GAAABCG2CYP2A6ALDH1A1 | |
| SCHEMBL5712397 | 0.81 | PRSS1 (0.46) | LOXL2GAAABCG2CYP2A6ALDH1A1 | |
| SCHEMBL6418566 | 0.81 | PRSS1 (0.46) | LOXL2GAAABCG2CYP2A6ALDH1A1 | |
| SCHEMBL8176730 | 0.80 | ABCB1 (0.52) | LOXL2GAAABCB1ABCG2CACNA1B | |
| SCHEMBL11500089 | 0.79 | MGLL (0.50) | LOXL2GAAABCB1ABCG2CYP2A6 | |
| SCHEMBL14255799 | 0.78 | LOXL2 (0.44) | LOXL2ABCC9KCNJ11KIF11CYP2A6 | |
| SCHEMBL5335241 | 0.78 | KCNH3 (0.41) | GAAALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL11250412 | 0.78 | EGLN2 (0.41) | KIF11ABCG2SLC22A12CA1CA2 | |
| SCHEMBL11289367 | 0.77 | MGLL (0.52) | LOXL2GAAABCB1ABCG2CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100160626-A1 | Process For The Preparation Of 3,7-Dihydroxy-1,5-Diazacyclooctanes | ASTRAZENECA AB (SE) | 2010-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100160626-A1 | Process For The Preparation Of 3,7-Dihydroxy-1,5-Diazacyclooctanes | CYP2D6, KCNH1, CYP2B6 | LOXL2 2857/4885ABCC9 1241/4885KCNJ11 57/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.