SCHEMBL133344

SCHEMBL133344

O=[PH]([O-])C[PH](=O)[O-].[Na+].[Na+]

nearest known ligand 0.00

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL441708 0.73
SCHEMBL6864380 0.70
SCHEMBL2975535 0.70
SCHEMBL3629397 0.70
Phosphonic Acid SCHEMBL124360 0.68
Phosphonic Acid SCHEMBL1168332 0.68
Phosphonic Acid SCHEMBL23674258 0.64
Phosphonic Acid SCHEMBL1167665 0.64
Phosphonic Acid SCHEMBL1204387 0.64
Phosphonic Acid SCHEMBL18422012 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 621 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9878984-B2 Anti-cancer compounds NORTHWESTERN UNIVERSITY (US) 2018-01-30 US claimed
US-20140378503-A1 ANTI-CANCER COMPOUNDS NORTHWESTERN UNIVERSITY 2014-12-25 US claimed
US-8829025-B2 Anti-cancer compounds NORTHWESTERN UNIVERSITY (US) 2014-09-09 US claimed
US-20130225634-A1 ANTI-CANCER COMPOUNDS NORTHWESTERN UNIVERSITY (US) 2013-08-29 US claimed
US-20100303719-A1 ANTI-CANCER COMPOUNDS NORTHWESTERN UNIVERSITY (US) 2010-12-02 US claimed
US-20090275099-A1 Methods and compositions for treating diseases and conditions associated with mitochondrial function REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2009-11-05 US claimed
WO-2009089537-A2 ANTI-CANCER COMPOUNDS NORTHWESTERN UNIVERSITY (US) 2009-07-16 WO claimed
US-20260091104-A1 NUCLEIC ACID VACCINES MODERNATX, INC. (US) 2026-04-02 US disclosed
EP-4712948-A2 GENE EDITING SYSTEMS AND COMPOSITIONS FOR TREATMENT OF HEMOGLOBINOPATHIES AND METHODS OF USING THE SAME Renagade Therapeutics Management Inc. (US) 2026-03-25 EP disclosed
US-20250312364-A1 METHODS FOR THE USE OF PSYCHEDELICS TRYP THERAPEUTICS INC. (CA) 2025-10-09 US disclosed
US-12403177-B2 Silk-based product formulations and methods of use COCOON BIOTECH INC. (US) 2025-09-02 US disclosed
US-12350375-B2 Method for obtaining efficient viral vector-based compositions for vaccination or gene therapy LEUKOCARE AG (DE) 2025-07-08 US disclosed
WO-2025049959-A9 GENE EDITING SYSTEMS, COMPOSITIONS, AND METHODS FOR TREATMENT OF VEXAS SYNDROME RENAGADE THERAPEUTICS MANAGEMENT INC. (US) 2025-06-12 WO disclosed
WO-2000067802-A1 FATTY ACID-N-SUBSTITUTED INDOL-3-GLYOXYL-AMIDE COMPOSITIONS AND USES THEREOF PROTARGA, INC. (US) 2000-11-16 WO disclosed
WO-2000053231-A2 FATTY ACID-ANTICANCER CONJUGATES AND USES THEREOF PROTARGA, INC. (US) 2000-09-14 WO disclosed
WO-1999036570-A2 TRANSGLUTAMINASE LINKAGE OF AGENTS TO TISSUE PERICOR SCIENCE INC (US) 1999-07-22 WO disclosed
WO-1999030690-A1 ORAL DELIVERY FORMULATION AXIA THERAPEUTICS, INC. (US) 1999-06-24 WO disclosed
EP-0909183-A2 DHA-PHARMACEUTICAL AGENT CONJUGATES Neuromedica, Inc. (US) 1999-04-21 EP disclosed
US-5795909-A ANTICARCINOGENIC AND ANTITUMOR AGENTS; BREAST, COLON, OVARIANCANCERS NEUROMEDICA, INC. (US) 1998-08-18 US disclosed
WO-1997044063-A2 DHA-PHARMACEUTICAL AGENT CONJUGATES NEUROMEDICA, INC. (US) 1997-11-27 WO disclosed