Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | PRKCA | P17252 | 1/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.35 |
| ▸ | ELANE | P08246 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GBA1 | P04062 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.31 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.31 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | BTN3A1 | O00481 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19742334 | 0.86 | POLB (0.41) | POLBGAANPSR1PRKCACYP4F2 | |
| SCHEMBL4258156 | 0.84 | POLB (0.48) | POLBGAANPSR1PRKCACYP4F2 | |
| SCHEMBL19857456 | 0.83 | CYP4F2 (0.31) | POLBGAANPSR1CYP4F2CYP4A11 | |
| SCHEMBL150006 | 0.82 | PRKCA (0.47) | POLBGAANPSR1PRKCACYP4F2 | |
| SCHEMBL19448898 | 0.82 | POLB (0.33) | POLBGAANPSR1PRKCA | |
| Ammonia Solution, Strong SCHEMBL27804637 | 0.80 | PRKCA (0.45) | POLBGAANPSR1PRKCACYP4F2 | |
| SCHEMBL7096949 | 0.80 | POLB (0.43) | POLBGAANPSR1PRKCACYP4F2 | |
| SCHEMBL2610375 | 0.79 | CYP4F2 (0.40) | CYP4F2CYP4A11 | |
| SCHEMBL18373345 | 0.79 | CYP4F2 (0.33) | CYP4F2CYP4A11 | |
| SCHEMBL7989588 | 0.79 | POLB (0.46) | POLBGAANPSR1PRKCACYP4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170373348-A1 | NONAQUEOUS ELECTROLYTIC SOLUTION AND ENERGY STORAGE DEVICE USING THE SAME | UBE INDUSTRIES, LTD (JP) | 2017-12-28 | — | — | US | claimed |
| US-12032290-B2 | Actinic ray-sensitive or radiation-sensitive resin composition, resist film, pattern forming method, and method for manufacturing electronic device | FUJIFILM CORPORATION (JP) | 2024-07-09 | — | — | US | disclosed |
| US-11802105-B2 | Treprostinil derivatives and compositions and uses thereof | Corsair Pharma, Inc. (US) | 2023-10-31 | — | — | US | disclosed |
| US-11639364-B2 | Potent sialyltransferase inhibitors | STICHTING RADBOUD UNIVERSITEIT (NL) | 2023-05-02 | — | — | US | disclosed |
| US-11639364-B2 | Potent sialyltransferase inhibitors | STICHTING RADBOUD UNIVERSITEIT (NL) | 2023-05-02 | — | — | US | disclosed |
| US-20230015308-A1 | SUBSTITUTED THIAZOLE AROMATIC RING-BASED COMPOUND AND PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION AND USE THEREOF | QINGDAO KINGAGROOT CHEMICAL COMPOUND CO., LTD. (CN) | 2023-01-19 | — | — | US | disclosed |
| US-20210107931-A1 | New potent sialyltransferase inhibitors | STICHTING KATHOLIEKE UNIVERSITEIT (NL) | 2021-04-15 | — | — | US | disclosed |
| US-20180170855-A1 | TREPROSTINIL DERIVATIVES AND COMPOSITIONS AND USES THEREOF | Corsair Pharma, Inc. | 2018-06-21 | — | — | US | disclosed |
| US-9957220-B2 | Treprostinil derivatives and compositions and uses thereof | Corsair Pharma, Inc. (US) | 2018-05-01 | — | — | US | disclosed |
| US-9873709-B2 | Triazolopyridine compounds, compositions and methods of use thereof | GENENTECH, INC. (US) | 2018-01-23 | — | — | US | disclosed |
| US-20170226132-A1 | TRIAZOLOPYRIDINE COMPOUNDS, COMPOSITIONS AND METHODS OF USE THEREOF | GENENTECH, INC. (US) | 2017-08-10 | — | — | US | disclosed |
| US-20170114246-A1 | BLOCK COPOLYMERS FOR DIRECTED SELF-ASSEMBLY APPLICATIONS | ELPIS TECHNOLOGIES INC. (CA) | 2017-04-27 | — | — | US | disclosed |
| US-9394227-B1 | Treprostinil derivatives and compositions and uses thereof | Corsair Pharma, Inc. (US) | 2016-07-19 | — | — | US | disclosed |
| US-8895583-B2 | Soluble guanylate cyclase activators | MERCK SHARP & DOHME CORP. (US) | 2014-11-25 | — | — | US | disclosed |
| US-20140057895-A1 | INDAZOLE- AND PYRROLOPYRIDINE-DERIVATIVE AND PHARMACEUTICAL USE THEREOF | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2014-02-27 | — | — | US | disclosed |
| US-20130210798-A1 | SOLUBLE GUANYLATE CYCLASE ACTIVATORS | MERCK SHARP & DOHME LLC | 2013-08-15 | — | — | US | disclosed |
| CN-102186890-B | Fluorine-containing sulfonates having polymerizable anions and manufacturing method therefor, fluorine-containing resins, resist compositions, and pattern-forming method using same | CENTRAL GLASS CO LTD | 2013-07-31 | — | — | CN | disclosed |
| CN-102186890-A | Fluorine-containing sulfonates having polymerizable anions and manufacturing method therefor, fluorine-containing resins, resist compositions, and pattern-forming method using same | CENTRAL GLASS CO LTD | 2011-09-14 | — | — | CN | disclosed |
| US-7446110-B2 | 17-Heterocyclic-4-azasteroid derivatives as androgen receptor modulators | MERCK & CO., INC. (US) | 2008-11-04 | — | — | US | disclosed |
| US-20070054933-A1 | 17-Heterocyclic-4-azasteroid derivatives as androgen receptor modulators | MERCK & CO., INC (US) | 2007-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210107931-A1 | New potent sialyltransferase inhibitors | NMT1, NEU1, NMT2 | POLB 4315/4885GAA 447/4885NPSR1 1483/4885 |
| US-20130210798-A1 | SOLUBLE GUANYLATE CYCLASE ACTIVATORS | GUCY1B1, GUCY1A1, GUCY1A2 | POLB 3659/4885GAA 990/4885NPSR1 2566/4885 |
| US-11802105-B2 | Treprostinil derivatives and compositions and uses thereof | PTGIS, PTGIR, PDE3A | POLB 758/4885GAA 1269/4885NPSR1 1252/4885 |
| US-20180170855-A1 | TREPROSTINIL DERIVATIVES AND COMPOSITIONS AND USES THEREOF | PTGIS, PTGIR, PDE3A | POLB 758/4885GAA 1269/4885NPSR1 1252/4885 |
| US-20230015308-A1 | SUBSTITUTED THIAZOLE AROMATIC RING-BASED COMPOUND AND PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION AND USE THEREOF | WEE1, CBR3, GLRX3 | POLB 3913/4885GAA 2047/4885NPSR1 2879/4885 |
| US-20140057895-A1 | INDAZOLE- AND PYRROLOPYRIDINE-DERIVATIVE AND PHARMACEUTICAL USE THEREOF | HTR4, HTR3B, HTR3A | POLB 2810/4885GAA 3565/4885NPSR1 67/4885 |
| US-20070054933-A1 | 17-Heterocyclic-4-azasteroid derivatives as androgen receptor modulators | AR, SHBG, NR5A1 | POLB 1817/4885GAA 2605/4885NPSR1 1751/4885 |
| US-20170226132-A1 | TRIAZOLOPYRIDINE COMPOUNDS, COMPOSITIONS AND METHODS OF USE THEREOF | ABL1, JAK2, JAK1 | POLB 2553/4885GAA 3271/4885NPSR1 1871/4885 |
| US-11639364-B2 | Potent sialyltransferase inhibitors | NEU1, NMT1, NEU2 | POLB 4243/4885GAA 412/4885NPSR1 1144/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.