SCHEMBL1337217

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21770975	0.87	XDH (0.51)	XDHADORA2AADORA1KCNH2SCN10A
	SCHEMBL5840598	0.85	SLC13A5 (0.51)	XDHSLC13A5ADORA2AADORA1KCNH2
	SCHEMBL2380991	0.84	XDH (0.49)	XDHSLC13A5ADORA2AADORA1KCNH2
	SCHEMBL5497159	0.83	KIF11 (0.47)	TAAR1XDHCYP3A4HSD17B10TDP1
	SCHEMBL1044062	0.82	CYP1A2 (0.51)	XDHSLC13A5KCNH2SCN10ADHODH
	SCHEMBL5379608	0.82	ESR1 (0.55)	XDHSLC13A5DHODHSLC6A7GALR1
	SCHEMBL30363971	0.82	ABL1 (0.54)	TAAR1CYP3A4KIF11
	SCHEMBL1241524	0.82	ABL1 (0.54)	TAAR1CYP3A4KIF11
	SCHEMBL5544749	0.82	SLC13A5 (0.47)	XDHSLC13A5KCNH2SCN10ADHODH
	SCHEMBL1337687	0.81	XDH (0.47)	XDHSLC13A5ADORA2AADORA1KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.