Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 1/20 | 0.85 |
| ▸ | TERT | O14746 | 3/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.56 |
| ▸ | PPARG | P37231 | 3/20 | 0.56 |
| ▸ | PPARD | Q03181 | 3/20 | 0.56 |
| ▸ | PPARA | Q07869 | 3/20 | 0.56 |
| ▸ | TOP1 | P11387 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | BLM | P54132 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | FABP4 | P15090 | 2/20 | 0.56 |
| ▸ | F7 | P08709 | 2/20 | 0.56 |
| ▸ | F3 | P13726 | 2/20 | 0.56 |
| ▸ | GMNN | O75496 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28101613 | 1.00 | ACLY (0.85) | ACLYTERTPTPN1PPARGPPARD | |
| SCHEMBL1340692 | 1.00 | ACLY (0.85) | ACLYTERTPTPN1PPARGPPARD | |
| SCHEMBL6498499 | 1.00 | ACLY (0.85) | ACLYTERTPTPN1PPARGPPARD | |
| SCHEMBL3628647 | 1.00 | ACLY (0.85) | ACLYTERTPTPN1PPARGPPARD | |
| SCHEMBL3628649 | 1.00 | ACLY (0.85) | ACLYTERTPTPN1PPARGPPARD | |
| SCHEMBL6237605 | 1.00 | ACLY (0.85) | ACLYTERTPTPN1PPARGPPARD | |
| SCHEMBL29138961 | 0.98 | ACLY (0.82) | ACLYTERTPTPN1PPARGPPARD | |
| SCHEMBL13735034 | 0.95 | ACLY (0.77) | ACLYPPARGPPARDPPARAMAPT | |
| SCHEMBL3626408 | 0.95 | ACLY (0.77) | ACLYPPARGPPARDPPARAMAPT | |
| SCHEMBL11863724 | 0.95 | ACLY (0.77) | ACLYPPARGPPARDPPARAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190084903-A1 | CATALYTIC ETHENOLYSIS OF OPTIONALLY-FUNCTIONALIZED INTERNAL UNSATURATED OLEFINS | TOTAL RAFFINAGE CHIMIE (FR) | 2019-03-21 | — | — | US | disclosed |
| EP-3325147-A2 | CATALYTIC ETHENOLYSIS OF OPTIONALLY-FUNCTIONALIZED INTERNAL UNSATURATED OLEFINS | TOTAL RAFFINAGE CHIMIE (FR) | 2018-05-30 | — | — | EP | disclosed |
| WO-2017013062-A2 | CATALYTIC ETHENOLYSIS OF OPTIONALLY-FUNCTIONALIZED INTERNAL UNSATURATED OLEFINS | TOTAL MARKETING SERVICES (FR) | 2017-01-26 | — | — | WO | disclosed |
| EP-2498909-B1 | METATHESIS CATALYST AND PROCESS FOR USE THEREOF | EXXONMOBIL CHEM PATENTS INC (US) | 2014-08-27 | — | — | EP | disclosed |
| US-8329921-B2 | Metathesis catalyst and process for use thereof | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2012-12-11 | — | — | US | disclosed |
| EP-2498909-A2 | METATHESIS CATALYST AND PROCESS FOR USE THEREOF | ExxonMobil Chemical Patents Inc. (US) | 2012-09-19 | — | — | EP | disclosed |
| US-20110306815-A1 | Metathesis Catalyst and Process for Use Thereof | EXXONMOBIL CHEMICAL PATENTS INC. | 2011-12-15 | — | — | US | disclosed |
| US-8063232-B2 | Metathesis catalyst and process for use thereof | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2011-11-22 | — | — | US | disclosed |
| WO-2011056881-A2 | METATHESIS CATALYST AND PROCESS FOR USE THEREOF | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2011-05-12 | — | — | WO | disclosed |
| US-20110112305-A1 | METATHESIS CATALYST AND PROCESS FOR USE THEREOF | EXXONMOBIL CHEMICAL PATENTS INC. | 2011-05-12 | — | — | US | disclosed |
| EP-1377537-B1 | METATHESIS OF UNSATURATED FATTY ACID ESTERS OR UNSATURATED FATTY ACIDS WITH LOWER OLEFINS | DOW GLOBAL TECHNOLOGIES INC (US) | 2009-04-22 | — | — | EP | disclosed |
| US-7119216-B2 | Metathesis of unsaturated fatty acid esters or unsaturated fatty acids with lower olefins | DOW GLOBAL TECHNOLOGIES INC. (US) | 2006-10-10 | — | — | US | disclosed |
| US-20050070750-A1 | Metathesis of unsaturated fatty acid esters or unsaturated fatty acids with lower olefins | DOW GLOBAL TECHNOLOGIES LLC | 2005-03-31 | — | — | US | disclosed |
| EP-1377537-A1 | METATHESIS OF UNSATURATED FATTY ACID ESTERS OR UNSATURATED FATTY ACIDS WITH LOWER OLEFINS | DOW GLOBAL TECHNOLOGIES INC. (US) | 2004-01-07 | — | — | EP | disclosed |
| WO-2002076920-A1 | METATHESIS OF UNSATURATED FATTY ACID ESTERS OR UNSATURATED FATTY ACIDS WITH LOWER OLEFINS | DOW GLOBAL TECHNOLOGIES INC. (US) | 2002-10-03 | — | — | WO | disclosed |
| EP-0148752-B1 | PROTEASE INHIBITORS | G.D. Searle & Co. (US) | 1989-06-21 | — | — | EP | disclosed |
| US-4551279-A | Protease inhibitors | G. D. SEARLE & CO. (US) | 1985-11-05 | — | — | US | disclosed |
| EP-0148752-A2 | Protease inhibitors | G.D. Searle & Co. (US) | 1985-07-17 | — | — | EP | disclosed |
| US-4477497-A | HEATING THE FIBER COATED WITH A FINISH CONTAINING A LUBRICANT, EPOXY COMPOUND AND A NOVOLAK | UNITIKA LIMITED (US) | 1984-10-16 | — | — | US | disclosed |
| US-4467064-A | Method of manufacturing polyester fibers with good adhesion to rubber | UNITIKA LTD. (JP) | 1984-08-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050070750-A1 | Metathesis of unsaturated fatty acid esters or unsaturated fatty acids with lower olefins | ALOX12, ALOX15, ALOX5 | ACLY 1355/4885TERT 2467/4885PTPN1 4875/4885 |
| US-20190084903-A1 | CATALYTIC ETHENOLYSIS OF OPTIONALLY-FUNCTIONALIZED INTERNAL UNSATURATED OLEFINS | ALOX12, ELOVL1, ELOVL3 | ACLY 873/4885TERT 2260/4885PTPN1 4845/4885 |
| US-20110306815-A1 | Metathesis Catalyst and Process for Use Thereof | MGLL, FASN, ABHD6 | ACLY 361/4885TERT 1096/4885PTPN1 4442/4885 |
| US-20110112305-A1 | METATHESIS CATALYST AND PROCESS FOR USE THEREOF | MGLL, FASN, ABHD6 | ACLY 361/4885TERT 1096/4885PTPN1 4442/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.