Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMD14 | O00487 | 4/20 | 0.40 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12128843 | 0.80 | LMNA (0.45) | PSMD14COPS5HIF1ACYP2C19LMNA | |
| SCHEMBL12131703 | 0.77 | HTR1A (0.53) | PSMD14COPS5LMNAL3MBTL1NPC1 | |
| SCHEMBL4364047 | 0.76 | KDM4E (0.49) | PSMD14COPS5HIF1ALMNAL3MBTL1 | |
| SCHEMBL26971200 | 0.76 | PSMD14 (0.40) | PSMD14COPS5HIF1ACYP2C19LMNA | |
| SCHEMBL2963509 | 0.76 | PSMD14 (0.45) | PSMD14HIF1ALMNAIDO1L3MBTL1 | |
| SCHEMBL23479346 | 0.76 | NR4A2 (0.56) | PSMD14COPS5LMNAL3MBTL1NPC1 | |
| SCHEMBL21173367 | 0.76 | PARP1 (0.41) | PSMD14COPS5ADORA2AADORA1LMNA | |
| SCHEMBL25636281 | 0.73 | NCF1 (0.49) | PSMD14COPS5CYP2C19ADORA2AADORA1 | |
| SCHEMBL24392332 | 0.73 | HTR1A (0.56) | HTR1AADRA1DADRA1AADRA1BHPGD | |
| SCHEMBL13201607 | 0.73 | SLC40A1 (0.47) | PSMD14L3MBTL1NPC1HSP90AA1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7705146-B2 | Hepatitis C inhibitor peptide analogs | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-04-27 | — | — | US | disclosed |
| US-7705146-B2 | Hepatitis C inhibitor peptide analogs | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-04-27 | — | — | US | disclosed |