Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 6/20 | 0.41 |
| ▸ | FDFT1 | P37268 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | PPARA | Q07869 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13416241 | 0.89 | ACHE (0.41) | ACHEFDFT1LMNAMTNR1AMTNR1B | |
| SCHEMBL13416411 | 0.87 | ACHE (0.40) | ACHEFDFT1LMNAMTNR1AMTNR1B | |
| SCHEMBL13416630 | 0.85 | LTA4H (0.39) | ACHEFDFT1PPARGPPARA | |
| SCHEMBL14135115 | 0.85 | ACHE (0.44) | ACHEFDFT1 | |
| SCHEMBL13416081 | 0.84 | ACHE (0.42) | ACHELMNA | |
| SCHEMBL13416287 | 0.83 | ACHE (0.43) | ACHEMTNR1AMTNR1BPPARGPPARA | |
| SCHEMBL13416257 | 0.82 | ACHE (0.43) | ACHE | |
| SCHEMBL13396514 | 0.82 | ALOX5 (0.39) | ACHEFDFT1LMNAMTNR1AMTNR1B | |
| SCHEMBL13416894 | 0.80 | MTNR1A (0.39) | ACHEFDFT1MTNR1AMTNR1B | |
| SCHEMBL13416416 | 0.80 | ACHE (0.41) | ACHEFDFT1PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100099729-A1 | NITRIC OXIDE DONOR COMPOUNDS | NICOX S.A. (FR) | 2010-04-22 | — | — | US | disclosed |
| WO-2008095841-A2 | NITRIC OXIDE DONOR COMPOUNDS | NICOX S.A. (FR) | 2008-08-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100099729-A1 | NITRIC OXIDE DONOR COMPOUNDS | NOS3, NOS2, NOS1 | ACHE 540/4885FDFT1 1243/4885LMNA 4585/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.