Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 9/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | MME | P08473 | 2/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13416579 | 0.87 | CA2 (0.37) | CASP1CA2CA4MME | |
| SCHEMBL13416655 | 0.87 | TGFBR1 (0.39) | CA2MME | |
| SCHEMBL13417041 | 0.86 | FOLH1 (0.46) | FOLH1 | |
| SCHEMBL13416684 | 0.84 | ALDH1A1 (0.46) | FOLH1MAPT | |
| SCHEMBL13416910 | 0.83 | — | — | |
| SCHEMBL16124634 | 0.82 | CASP1 (0.39) | CASP1CA2CA4MMEFOLH1 | |
| SCHEMBL13416663 | 0.81 | FOLH1 (0.42) | FOLH1 | |
| SCHEMBL13416718 | 0.81 | PPARG (0.31) | — | |
| SCHEMBL13416903 | 0.80 | FOLH1 (0.45) | CA2FOLH1 | |
| SCHEMBL13416686 | 0.80 | LMNA (0.40) | CA2FOLH1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100099729-A1 | NITRIC OXIDE DONOR COMPOUNDS | NICOX S.A. (FR) | 2010-04-22 | — | — | US | disclosed |
| WO-2008095841-A2 | NITRIC OXIDE DONOR COMPOUNDS | NICOX S.A. (FR) | 2008-08-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100099729-A1 | NITRIC OXIDE DONOR COMPOUNDS | NOS3, NOS2, NOS1 | CASP1 1575/4885CA2 2652/4885CA4 4156/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.