Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAALAD2 | Q9Y3Q0 | 4/20 | 0.43 |
| ▸ | TMPRSS15 | P98073 | 4/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 10/20 | 0.41 |
| ▸ | SELP | P16109 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.39 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13417042 | 0.93 | SELP (0.45) | NAALAD2TMPRSS15FOLH1SELPPRSS1 | |
| SCHEMBL13416590 | 0.88 | TMPRSS15 (0.41) | TMPRSS15PRSS1 | |
| SCHEMBL13416587 | 0.87 | ITGB1 (0.39) | TMPRSS15PRSS1GAA | |
| SCHEMBL13417046 | 0.87 | NAALAD2 (0.44) | NAALAD2FOLH1SELPGAA | |
| SCHEMBL13416691 | 0.85 | ALDH1A1 (0.46) | — | |
| SCHEMBL13416909 | 0.85 | ITGB3 (0.44) | FOLH1PRSS1 | |
| SCHEMBL13416664 | 0.84 | TGM2 (0.45) | FOLH1GAA | |
| SCHEMBL13416682 | 0.84 | MAPT (0.44) | FOLH1 | |
| SCHEMBL13396892 | 0.82 | NAALAD2 (0.41) | NAALAD2TMPRSS15FOLH1SELPPRSS1 | |
| SCHEMBL13416583 | 0.81 | CASP1 (0.43) | TMPRSS15PRSS1FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100099729-A1 | NITRIC OXIDE DONOR COMPOUNDS | NICOX S.A. (FR) | 2010-04-22 | — | — | US | disclosed |
| WO-2008095841-A2 | NITRIC OXIDE DONOR COMPOUNDS | NICOX S.A. (FR) | 2008-08-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100099729-A1 | NITRIC OXIDE DONOR COMPOUNDS | NOS3, NOS2, NOS1 | NAALAD2 1509/4885TMPRSS15 2014/4885FOLH1 2259/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.