Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.32 |
| ▸ | PPARG | P37231 | 2/20 | 0.32 |
| ▸ | PPARA | Q07869 | 2/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL275277 | 0.75 | CALM1 (0.43) | TDP1ALDH1A1CALM1HPGDALOX15 | |
| SCHEMBL13994371 | 0.67 | PLA2G1B (0.40) | ALDH1A1CALM1PPARGPPARAKMT2A | |
| SCHEMBL2686945 | 0.67 | TAAR1 (0.41) | PPARGPPARAP2RX7MEN1KMT2A | |
| SCHEMBL3196407 | 0.64 | ALOX5 (0.53) | MEN1KMT2AHIF1A | |
| SCHEMBL10665160 | 0.63 | TSHR (0.58) | ALDH1A1CYP3A4HPGDHIF1AHSD17B10 | |
| SCHEMBL6347147 | 0.63 | LMNA (0.42) | TDP1ALDH1A1MEN1KMT2ACYP3A4 | |
| SCHEMBL6349027 | 0.63 | PLA2G1B (0.40) | ALDH1A1 | |
| SCHEMBL11344330 | 0.62 | CALM1 (0.50) | TDP1ALDH1A1CALM1HPGDALOX15 | |
| SCHEMBL4458296 | 0.61 | AHR (0.64) | ALDH1A1HSP90AA1MEN1KMT2ACYP3A4 | |
| (Chloromethyl)Benzene SCHEMBL11741126 | 0.61 | DRD2 (0.44) | SIGMAR1P2RX7TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7671055-B2 | surprisingly active in the control of insects and acarids; admixture with pesticides, plant growth regulators, fertilizers and soil conditioners | FMC CORPORATION (US) | 2010-03-02 | — | — | US | disclosed |
| US-7671055-B2 | surprisingly active in the control of insects and acarids; admixture with pesticides, plant growth regulators, fertilizers and soil conditioners | FMC CORPORATION (US) | 2010-03-02 | — | — | US | disclosed |
| US-20080261993-A1 | Insecticidal 3-(Dihaloalkenyl) Phenyl Derivatives | BAYER CROPSCIENCE AG (DE) | 2008-10-23 | — | — | US | disclosed |
| US-20080261993-A1 | Insecticidal 3-(Dihaloalkenyl) Phenyl Derivatives | BAYER CROPSCIENCE AG (DE) | 2008-10-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080261993-A1 | Insecticidal 3-(Dihaloalkenyl) Phenyl Derivatives | DDT, L3MBTL4, L3MBTL3 | SIGMAR1 2674/4885TDP1 1665/4885ALDH1A1 1084/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.