Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | XPO1 | O14980 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | XBP1 | P17861 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.34 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17908109 | 0.81 | S1PR2 (0.32) | MAPKAPK2ALDH1A1TDP1 | |
| SCHEMBL12130919 | 0.74 | MAPKAPK2 (0.33) | MAPKAPK2ALDH1A1 | |
| SCHEMBL4019648 | 0.74 | MAPKAPK2 (0.35) | MAPKAPK2ALDH1A1NPC1MAPK1RAB9A | |
| SCHEMBL30398825 | 0.74 | ALDH1A1 (0.40) | MAPKAPK2NPSR1ALDH1A1MAPTNPC1 | |
| SCHEMBL19816108 | 0.74 | ALDH1A1 (0.40) | MAPKAPK2NPSR1ALDH1A1MAPTNPC1 | |
| SCHEMBL17372766 | 0.73 | DPP4 (0.34) | XPO1ALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL18832296 | 0.72 | CASP1 (0.37) | NPSR1XPO1CASP1ALDH1A1MAPT | |
| SCHEMBL28048176 | 0.72 | AGBL2 (0.42) | MAPKAPK2ALDH1A1MAPTMAPK1KDM4E | |
| SCHEMBL18832311 | 0.71 | PDE4D (0.42) | NPSR1XPO1CASP1ALDH1A1MAPT | |
| SCHEMBL16606973 | 0.70 | RAB9A (0.40) | ALDH1A1NPC1MAPK1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2396337-B1 | PREPARATION AND USE OF ZINC-AMIDES | UNIV MUENCHEN LUDWIG MAXIMILIANS (DE) | 2016-07-13 | — | — | EP | claimed |
| EP-2396337-A1 | PRODUCTION AND USE OF ZINC AMIDES | Ludwig-Maximilians-Universität München (DE) | 2011-12-21 | — | — | EP | claimed |
| US-20110288296-A1 | PRODUCTION AND USE OF ZINC AMIDES | LUDWIG-MAXIMILIANS-UNIVERSITÄT MÜNCHEN (DE) | 2011-11-24 | — | — | US | claimed |
| WO-2010092096-A1 | PRODUCTION AND USE OF ZINC AMIDES | LUDWIG-MAXIMILIANS-UNIVERSITÄT MÜNCHEN (DE) | 2010-08-19 | — | — | WO | claimed |
| US-9688701-B2 | Production and use of zinc amides | LUDWIG-MAXIMILIANS-UNIVERSITAT MUNCHEN (DE) | 2017-06-27 | — | — | US | disclosed |
| US-9688701-B2 | Production and use of zinc amides | LUDWIG-MAXIMILIANS-UNIVERSITAT MUNCHEN (DE) | 2017-06-27 | — | — | US | disclosed |
| US-9688701-B2 | Production and use of zinc amides | LUDWIG-MAXIMILIANS-UNIVERSITAT MUNCHEN (DE) | 2017-06-27 | — | — | US | disclosed |
| US-20160215000-A1 | Production And Use Of Zinc Amides | UNIV MUENCHEN LUDWIG MAXIMILIANS (DE) | 2016-07-28 | — | — | US | disclosed |
| US-20160215000-A1 | Production And Use Of Zinc Amides | UNIV MUENCHEN LUDWIG MAXIMILIANS (DE) | 2016-07-28 | — | — | US | disclosed |
| US-20160215000-A1 | Production And Use Of Zinc Amides | UNIV MUENCHEN LUDWIG MAXIMILIANS (DE) | 2016-07-28 | — | — | US | disclosed |
| EP-2396337-B1 | PREPARATION AND USE OF ZINC-AMIDES | UNIV MUENCHEN LUDWIG MAXIMILIANS (DE) | 2016-07-13 | — | — | EP | disclosed |
| EP-2396337-B1 | PREPARATION AND USE OF ZINC-AMIDES | UNIV MUENCHEN LUDWIG MAXIMILIANS (DE) | 2016-07-13 | — | — | EP | disclosed |
| US-9334237-B2 | Production and use of zinc amides | LUDWIG-MAXIMILIANS-UNIVERSITAT MUNCHEN (DE) | 2016-05-10 | — | — | US | disclosed |
| US-9334237-B2 | Production and use of zinc amides | LUDWIG-MAXIMILIANS-UNIVERSITAT MUNCHEN (DE) | 2016-05-10 | — | — | US | disclosed |
| WO-2015047124-A1 | NOVEL CHEMICAL COMPOUNDS DERIVED FROM 2,4-DIAMINO-1,3,5-TRIAZINE FOR THE PROPHYLAXIS AND TREATMENT OF HUMAN AND ANIMAL DISEASES | Общество с ограниченной ответственностью "Молекулярные Технологии" | 2015-04-02 | — | — | WO | disclosed |
| EP-2396337-A1 | PRODUCTION AND USE OF ZINC AMIDES | Ludwig-Maximilians-Universität München (DE) | 2011-12-21 | — | — | EP | disclosed |
| US-20110288296-A1 | PRODUCTION AND USE OF ZINC AMIDES | LUDWIG-MAXIMILIANS-UNIVERSITÄT MÜNCHEN (DE) | 2011-11-24 | — | — | US | disclosed |
| US-20110288296-A1 | PRODUCTION AND USE OF ZINC AMIDES | LUDWIG-MAXIMILIANS-UNIVERSITÄT MÜNCHEN (DE) | 2011-11-24 | — | — | US | disclosed |
| US-20110288296-A1 | PRODUCTION AND USE OF ZINC AMIDES | LUDWIG-MAXIMILIANS-UNIVERSITÄT MÜNCHEN (DE) | 2011-11-24 | — | — | US | disclosed |
| WO-2010092096-A1 | PRODUCTION AND USE OF ZINC AMIDES | LUDWIG-MAXIMILIANS-UNIVERSITÄT MÜNCHEN (DE) | 2010-08-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160215000-A1 | Production And Use Of Zinc Amides | SCLY, CBR3, SCO2 | MAPKAPK2 3682/4885NPSR1 149/4885XPO1 3160/4885 |
| US-20110288296-A1 | PRODUCTION AND USE OF ZINC AMIDES | GLRX3, SCLY, SFXN1 | MAPKAPK2 4212/4885NPSR1 280/4885XPO1 3182/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.