Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 14/20 | 0.79 |
| ▸ | PGR | P06401 | 8/20 | 0.79 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.79 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.79 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.79 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.79 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.79 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.79 |
| ▸ | IL5 | P05113 | 1/20 | 0.79 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.79 |
| ▸ | AR | P10275 | 1/20 | 0.79 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.79 |
| ▸ | MMP9 | P14780 | 1/20 | 0.79 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.79 |
| ▸ | THPO | P40225 | 1/20 | 0.79 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.79 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.79 |
| ▸ | LMNA | P02545 | 1/20 | 0.79 |
| ▸ | BLM | P54132 | 1/20 | 0.79 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30777667 | 1.00 | NR3C1 (0.79) | NR3C1PGRCYP3A4HIF1ACYP2C9 | |
| SCHEMBL22601658 | 1.00 | NR3C1 (0.79) | NR3C1PGRCYP3A4HIF1ACYP2C9 | |
| SCHEMBL21302924 | 1.00 | NR3C1 (0.79) | NR3C1PGRCYP3A4HIF1ACYP2C9 | |
| SCHEMBL27071472 | 1.00 | NR3C1 (0.79) | NR3C1PGRCYP3A4HIF1ACYP2C9 | |
| SCHEMBL13654443 | 0.92 | NR3C1 (0.68) | NR3C1PGRCYP3A4HIF1ACYP2C9 | |
| SCHEMBL13524560 | 0.90 | NR3C1 (0.66) | NR3C1PGRCYP3A4HIF1ACYP2C9 | |
| SCHEMBL24622229 | 0.90 | NR3C1 (0.88) | NR3C1PGRCYP3A4HIF1ACYP2C9 | |
| SCHEMBL12314028 | 0.90 | NR3C1 (0.88) | NR3C1PGRCYP3A4HIF1ACYP2C9 | |
| SCHEMBL13652071 | 0.90 | NR3C1 (0.88) | NR3C1PGRCYP3A4HIF1ACYP2C9 | |
| Budesonide SCHEMBL21570019 | 0.89 | NR3C1 (1.00) | NR3C1PGRCYP3A4HIF1ACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11787834-B2 | Glucocorticoid receptor agonists | ELI LILLY AND COMPANY (US) | 2023-10-17 | — | — | US | disclosed |
| US-20230310634-A1 | ANTI-HUMAN VISTA ANTIBODIES AND USE THEREOF | IMMUNEXT INC (US) | 2023-10-05 | — | — | US | disclosed |
| US-10538551-B2 | Process for preparation of corticosteroids | CORAL DRUGS PVT. LTD. (IN) | 2020-01-21 | — | — | US | disclosed |
| US-10441597-B2 | Ciclesonide for the treatment of airway disease in horses | BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) | 2019-10-15 | — | — | US | disclosed |
| US-20190177361-A1 | NOVEL PROCESS FOR PREPARATION OF CORTICOSTEROIDS | CORAL DRUGS PVT. LTD. (IN) | 2019-06-13 | — | — | US | disclosed |
| US-10258634-B2 | Ciclesonide for the treatment of airway disease in horses | BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) | 2019-04-16 | — | — | US | disclosed |
| US-10233210-B2 | Process for preparation of glucocorticoid steroids | CORAL DRUGS PVT. LTD. (IN) | 2019-03-19 | — | — | US | disclosed |
| US-20180153907-A1 | Ciclesonide for the Treatment of Airway Disease in Horses | BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) | 2018-06-07 | — | — | US | disclosed |
| US-9918995-B2 | Ciclesonide for the treatment of airway disease in horses | BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) | 2018-03-20 | — | — | US | disclosed |
| US-20170079988-A1 | CICLESONIDE FOR THE TREATMENT OF AIRWAY DISEASE IN HORSES | BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) | 2017-03-23 | — | — | US | disclosed |
| US-7645747-B2 | Improved pharmacokinetic properties, oral bioavailability; side effect reduction | GILEAD SCIENCES, INC. (US) | 2010-01-12 | — | — | US | disclosed |
| US-20090247488-A1 | ANTI-INFLAMMATORY PHOSPHONATE COMPOUNDS | CANNIZZARO CARINA | 2009-10-01 | — | — | US | disclosed |
| US-20090227543-A1 | PHOSPHONATE COMPOUNDS HAVING IMMUNO-MODULATORY ACTIVITY | CANNIZZARO CARINA | 2009-09-10 | — | — | US | disclosed |
| US-7470724-B2 | Phosphonate compounds having immuno-modulatory activity | GILEAD SCIENCES, INC. (US) | 2008-12-30 | — | — | US | disclosed |
| US-7432261-B2 | Anti-inflammatory phosphonate compounds | GILEAD SCIENCES, INC. (US) | 2008-10-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10538551-B2 | Process for preparation of corticosteroids | HSD17B7, NR3C2, CYP21A2 | NR3C1 17/4885PGR 56/4885CYP3A4 99/4885 |
| US-20090227543-A1 | PHOSPHONATE COMPOUNDS HAVING IMMUNO-MODULATORY ACTIVITY | PHOSPHO1, NFATC1, IFNG | NR3C1 1066/4885PGR 3296/4885CYP3A4 3919/4885 |
| US-10258634-B2 | Ciclesonide for the treatment of airway disease in horses | HSD11B2, CYP27B1, IL17A | NR3C1 18/4885PGR 1456/4885CYP3A4 2168/4885 |
| US-20180153907-A1 | Ciclesonide for the Treatment of Airway Disease in Horses | NR3C2, NR3C1, TSLP | NR3C1 2/4885PGR 2125/4885CYP3A4 2413/4885 |
| US-11787834-B2 | Glucocorticoid receptor agonists | NR3C1, NR3C2, MC2R | NR3C1 1/4885PGR 245/4885CYP3A4 911/4885 |
| US-20190177361-A1 | NOVEL PROCESS FOR PREPARATION OF CORTICOSTEROIDS | HSD17B7, NR3C2, CYP11B1 | NR3C1 18/4885PGR 53/4885CYP3A4 96/4885 |
| US-20090247488-A1 | ANTI-INFLAMMATORY PHOSPHONATE COMPOUNDS | PHOSPHO1, TNF, PTGES | NR3C1 310/4885PGR 1197/4885CYP3A4 1894/4885 |
| US-10441597-B2 | Ciclesonide for the treatment of airway disease in horses | NR3C2, NR3C1, TSLP | NR3C1 2/4885PGR 2125/4885CYP3A4 2413/4885 |
| US-20170079988-A1 | CICLESONIDE FOR THE TREATMENT OF AIRWAY DISEASE IN HORSES | HSD11B2, CYP27B1, IL17A | NR3C1 18/4885PGR 1456/4885CYP3A4 2168/4885 |
| US-10233210-B2 | Process for preparation of glucocorticoid steroids | CYP21A2, NR3C2, NR3C1 | NR3C1 3/4885PGR 65/4885CYP3A4 52/4885 |
| US-20230310634-A1 | ANTI-HUMAN VISTA ANTIBODIES AND USE THEREOF | CD47, CLTA, FCGR2A | NR3C1 104/4885PGR 2891/4885CYP3A4 3750/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.