SCHEMBL135348

SCHEMBL135348

Cc1ccc([B-](c2ccc(C)cc2)(c2ccc(C)cc2)c2ccc(C)cc2)cc1.[Na+]

nearest known ligand 0.53

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 known ✓ P00918 2/20 0.40
CA1 known ✓ P00915 1/20 0.40
ACHE P22303 6/20 0.53
TDP1 Q9NUW8 1/20 0.53
ALDH1A1 P00352 4/20 0.40
CA7 P43166 1/20 0.40
CA9 Q16790 1/20 0.40
TSHR P16473 3/20 0.37
LMNA P02545 2/20 0.37
ALOX12 P18054 1/20 0.37
CYP2A6 P11509 2/20 0.35
IDO1 P14902 1/20 0.35
CES2 O00748 1/20 0.35
CES1 P23141 1/20 0.35
LPL P06858 1/20 0.35
LIPG Q9Y5X9 1/20 0.35
ORAI1 Q96D31 1/20 0.35
ORAI2 Q96SN7 1/20 0.35
ORAI3 Q9BRQ5 1/20 0.35
TRPV6 Q9H1D0 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL473142 0.97 ACHE (0.57) ACHETDP1ALDH1A1CA2CA1
SCHEMBL15452890 0.93 ACHE (0.53) ACHETDP1ALDH1A1CA2CA1
Lithium Ion SCHEMBL136304 0.93 ACHE (0.53) ACHETDP1ALDH1A1CA2CA1
Potassium Ion SCHEMBL133256 0.93 ACHE (0.53) ACHETDP1ALDH1A1CA2CA1
SCHEMBL15452864 0.93 ACHE (0.53) ACHETDP1ALDH1A1CA2CA1
Ammonia Solution, Strong SCHEMBL26908485 0.93 ACHE (0.53) ACHETDP1ALDH1A1CA2CA1
SCHEMBL21810715 0.89 ACHE (0.50) ACHETDP1ALDH1A1TSHRLMNA
SCHEMBL21810702 0.89 ACHE (0.50) ACHETDP1ALDH1A1TSHRLMNA
Trimethylammonium SCHEMBL139184 0.88 ACHE (0.47) ACHETDP1ALDH1A1CA2CA1
SCHEMBL20723409 0.88 ACHE (0.47) ACHETDP1ALDH1A1CA2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 687 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11193915-B2 Composite material for the detection of chemical species INSTITUT NATIONAL D'OPTIQUE (CA) 2021-12-07 US claimed
US-20190017978-A1 COMPOSITE MATERIAL FOR THE DETECTION OF CHEMICAL SPECIES INSTITUT NATIONAL D'OPTIQUE (CA) 2019-01-17 US claimed
EP-3239190-A2 POLYMERIZATION CATALYSTS FOR PRODUCING POLYMERS WITH LOW LEVELS OF LONG CHAIN BRANCHING Chevron Phillips Chemical Company LP (US) 2017-11-01 EP claimed
WO-2017088069-A1 COMPOSITE MATERIAL FOR THE DETECTION OF CHEMICAL SPECIES INSTITUT NATIONAL D'OPTIQUE (CA) 2017-06-01 WO claimed
EP-2235069-B1 NANO-LINKED METALLOCENE CATALYST COMPOSITIONS AND THEIR POLYMER PRODUCTS CHEVRON PHILLIPS CHEMICAL CO (US) 2015-11-25 EP claimed
EP-2231717-B1 NANO-LINKED METALLOCENE CATALYST COMPOSITIONS AND THEIR POLYMER PRODUCTS CHEVRON PHILLIPS CHEMICAL CO (US) 2015-10-21 EP claimed
EP-2231716-B1 NANO-LINKED METALLOCENE CATALYST COMPOSITIONS AND THEIR POLYMER PRODUCTS CHEVRON PHILLIPS CHEMICAL CO (US) 2014-04-16 EP claimed
US-8524626-B2 Nano-linked metallocene catalyst compositions and their polymer products CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2013-09-03 US claimed
US-8329833-B2 Nano-linked metallocene catalyst compositions and their polymer products CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2012-12-11 US claimed
US-20120149855-A1 Nano-Linked Metallocene Catalyst Compositions and Their Polymer Products CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2012-06-14 US claimed
US-20050113243-A1 Catalyst compositions for producing polyolefins in the absence of cocatalysts CHEVRON PHILLIPS CHEMICAL COMPANY, LP 2005-05-26 US claimed
EP-0490300-B1 Process for the production of surface-modified electrophotographic toner particles NIPPON PAINT CO LTD (JP) 1998-03-25 EP claimed
EP-0548826-B1 Diallyl ammonium-compounds, method for their preparation and their application HOECHST AG (DE) 1997-04-23 EP claimed
EP-0476648-B1 Polymeric ammonium borates and process for their preparation HOECHST AG (DE) 1995-06-21 EP claimed
EP-0393504-B1 Phosphonium compounds and process for their preparation HOECHST AG (DE) 1994-10-26 EP claimed
EP-0507824-B1 BISCATIONIC ACID AMIDE AND ACID IMIDE DERIVATIVES AND PROCESS FOR PREPARING THEM HOECHST AG (DE) 1994-10-19 EP claimed
US-5329046-A Compounds with boron anions for charge control toners and developers for electrographic recording and charge controllers HOECHST AKTIENGESELLSCHAFT (DE) 1994-07-12 US claimed
US-5190844-A Electrophotographic toner NIPPON PAINT CO., LTD. (JP) 1993-03-02 US claimed
EP-0367164-B1 AMMONIUM AND IMMONIUM COMPOUNDS AND PROCESS FOR THEIR PREPARATION HOECHST AKTIENGESELLSCHAFT (DE) 1993-02-24 EP claimed
EP-0490300-A1 Production of surface-modified organic particles Nippon Paint Co., Ltd. (JP) 1992-06-17 EP claimed