SCHEMBL1354040

SCHEMBL1354040

C=C(C)CCC(=Cc1ccc(OC)cc1)C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.45
THRB P10828 2/20 0.45
NPC1 O15118 1/20 0.44
RAB9A P51151 1/20 0.44
ATM Q13315 1/20 0.44
GSK3B P49841 2/20 0.43
AKR1C3 P42330 1/20 0.43
ALDH1A1 P00352 3/20 0.42
KDM4E B2RXH2 2/20 0.42
HPGD P15428 2/20 0.42
F3 P13726 1/20 0.41
CYP1A2 P05177 2/20 0.41
CYP3A4 P08684 2/20 0.41
NPSR1 Q6W5P4 2/20 0.41
TSHR P16473 1/20 0.41
NFKB1 P19838 1/20 0.41
APEX1 P27695 1/20 0.41
BLM P54132 1/20 0.41
PMP22 Q01453 1/20 0.41
LMNA P02545 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8153618 0.86 NPC1 (0.59) MAPTTHRBNPC1RAB9AATM
SCHEMBL8153624 0.86 NPC1 (0.59) MAPTTHRBNPC1RAB9AATM
SCHEMBL489474 0.83 ALOX5 (0.48) MAPTTHRBNPC1RAB9AATM
SCHEMBL8381808 0.82 TDP1 (0.43) MAPTTHRBNPC1RAB9AATM
SCHEMBL8157085 0.82 TDP1 (0.43) MAPTTHRBNPC1RAB9AATM
SCHEMBL8550978 0.81 MAPT (0.46) MAPTTHRBGSK3BAKR1C3ALDH1A1
SCHEMBL6367852 0.81 ALOX5 (0.58) MAPTTHRBNPC1RAB9AATM
SCHEMBL8156581 0.80 POLB (0.47) MAPTTHRBNPC1RAB9AAKR1C3
SCHEMBL6659979 0.80 MAPT (0.50) MAPTTHRBNPC1RAB9AATM
SCHEMBL285248 0.80 MAPT (0.50) MAPTTHRBNPC1RAB9AATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 252 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250107974-A1 MICROCAPSULES COMPRISING SUNSCREEN AGENTS TAGRA BIOTECHNOLOGIES LTD. (IL) 2025-04-03 US claimed
EP-3233027-B1 COMPOSITIONS FOR PROVIDING IMPROVED SUNSCREEN PROTECTION UNILEVER IP HOLDINGS B V (NL) 2021-10-13 EP claimed
US-20180161263-A1 COMPOSITIONS FOR PROVIDING IMPROVED SUNSCREEN PROTECTION CONOPCO, INC., D/B/A UNILEVER (US) 2018-06-14 US claimed
US-9993559-B2 N-alkyl lactam ethers, and compositions and uses thereof ISP INVESTMENTS LLC (US) 2018-06-12 US claimed
US-9914795-B2 Polymers polymerized from at least four monomers, and compositions and uses thereof ISP INVESTMENTS LLC (US) 2018-03-13 US claimed
EP-3233027-A1 COMPOSITIONS FOR PROVIDING IMPROVED SUNSCREEN PROTECTION Unilever PLC (GB) 2017-10-25 EP claimed
US-9724544-B2 Vitamin D promoting sunscreen Armstrong, Ernest T. (US) 2017-08-08 US claimed
US-20160271254-A1 N-ALKYL LACTAM ETHERS, AND COMPOSITIONS AND USES THEREOF ISP INVESTMENTS INC. (US) 2016-09-22 US claimed
EP-1594454-B1 FILM FORMING HYDROALCOHOLIC FOAM STIEFEL RES AUSTRALIA PTY LTD (AU) 2016-07-27 EP claimed
WO-2016096344-A1 COMPOSITIONS FOR PROVIDING IMPROVED SUNSCREEN PROTECTION UNILEVER PLC (GB) 2016-06-23 WO claimed
US-20120237466-A1 PHOTO-FILTERING COMPOSITION FOR HAIR AND SCALP GRAHAM JAMES (US) 2012-09-20 US claimed
EP-2480498-A1 A PARTICULATE FLUORESCER AND A PROCESS FOR PREPARING THE SAME Unilever NV (NL) 2012-08-01 EP claimed
US-20120148514-A1 N-ALKYL LACTAM ETHERS, AND COMPOSITIONS AND USES THEREOF ISP INVESTMENTS INC. (US) 2012-06-14 US claimed
WO-2012068001-A1 N-ALKYL LACTAM ETHERS, AND COMPOSITIONS AND USES THEREOF ISP INVESTMENTS INC. (US) 2012-05-24 WO claimed
US-20120100183-A1 Topical base and active agent-containing compositions, and methods for improving and treating skin SCHLESSINGER JOEL (US) 2012-04-26 US claimed
WO-2012054071-A1 TOPICAL BASE AND ACTIVE AGENT-CONTAINING COMPOSITIONS, AND METHODS FOR IMPROVING AND TREATING SKIN SCHLESSINGER MD JOEL (US) 2012-04-26 WO claimed
US-20110212040-A1 STABILIZED SUNSCREEN COMPOSITIONS IBR ISRAELI BIOTECHNOLOGY RESEARCH LTD (IL) 2011-09-01 US claimed
WO-2011036029-A1 A PARTICULATE FLUORESCER AND A PROCESS FOR PREPARING THE SAME UNILEVER NV (NL) 2011-03-31 WO claimed
US-20060233727-A9 Film foaming hydroalcoholic foam CONNETICS AUSTRALIA PTY LTD. (AU) 2006-10-19 US claimed
US-20060067894-A1 Film foaming hydroalcoholic foam CONNETICS AUSTRALIA PTY LTD. (AU) 2006-03-30 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120100183-A1 Topical base and active agent-containing compositions, and methods for improving and treating skin TAF1L, TAS2R42, TAS2R38 MAPT 1116/4885THRB 69/4885NPC1 3113/4885
US-20250107974-A1 MICROCAPSULES COMPRISING SUNSCREEN AGENTS CUTA, HSF1, MITF MAPT 40/4885THRB 4515/4885NPC1 1689/4885
US-20160271254-A1 N-ALKYL LACTAM ETHERS, AND COMPOSITIONS AND USES THEREOF USP8, MLST8, CYP2C8 MAPT 1090/4885THRB 3698/4885NPC1 1352/4885
US-20120148514-A1 N-ALKYL LACTAM ETHERS, AND COMPOSITIONS AND USES THEREOF USP8, MLST8, CYP2C8 MAPT 1090/4885THRB 3698/4885NPC1 1352/4885
US-20120237466-A1 PHOTO-FILTERING COMPOSITION FOR HAIR AND SCALP CUTA, PTMA, GYPA MAPT 2428/4885THRB 638/4885NPC1 3107/4885
US-20180161263-A1 COMPOSITIONS FOR PROVIDING IMPROVED SUNSCREEN PROTECTION DSG1, GALE, UGGT1 MAPT 963/4885THRB 4231/4885NPC1 3671/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.