SCHEMBL22731985

SCHEMBL22731985

C=C/C(=C\C=C(/C)C=C1c2ccc(O)cc2Oc2cc(O)ccc21)CN

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ TYR P14679 1/20 0.31
▸ MAOA P21397 1/20 0.31
▸ MAOB P27338 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22731771 0.94 MEN1 (0.31) TYRMAOAMAOB
SCHEMBL13542765 0.64 TYR (0.40) TYRMAOAMAOB
SCHEMBL20099452 0.62 CRHBP (0.44) TYRMAOAMAOB
SCHEMBL22046626 0.62 MAOB (0.48) TYRMAOAMAOB
SCHEMBL23460330 0.60 MAOA (0.43) TYRMAOAMAOB
SCHEMBL29919352 0.60 MAOA (0.43) TYRMAOAMAOB
SCHEMBL8845451 0.59 MAOB (0.41) TYRMAOAMAOB
SCHEMBL20862990 0.58 — —
SCHEMBL22332053 0.58 — —
SCHEMBL22046148 0.57 MAOB (0.43) TYRMAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11821901-B2 Styryl phenols, derivatives and their use in methods of analyte detection AAT BIOQUEST, INC. (US) 2023-11-21 — — US disclosed
US-20200378975-A1 STYRYL PHENOLS, DERIVATIVES AND THEIR USE IN METHODS OF ANALYTE DETECTION AAT BIOQUEST, INC. (US) 2020-12-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11821901-B2 Styryl phenols, derivatives and their use in methods of analyte detection STUB1, SPR, HLCS TYR 72/4885MAOA 1625/4885MAOB 272/4885
US-20200378975-A1 STYRYL PHENOLS, DERIVATIVES AND THEIR USE IN METHODS OF ANALYTE DETECTION STUB1, SPR, HLCS TYR 72/4885MAOA 1625/4885MAOB 272/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback