Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 2/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.34 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.34 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.34 |
| ▸ | ITGAL | P20701 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6491384 | 0.84 | OPRD1 (0.51) | OPRD1OPRK1KCNH2TSHRNPC1 | |
| SCHEMBL6478605 | 0.81 | OPRD1 (0.36) | OPRD1OPRK1KCNH2PKMTSHR | |
| SCHEMBL6478611 | 0.81 | ELANE (0.39) | PKMTSHRKMT2AALDH1A1MAOB | |
| SCHEMBL20346473 | 0.79 | CYP19A1 (0.46) | TSHRKMT2ACYP19A1ALDH1A1MAPK1 | |
| SCHEMBL6492765 | 0.79 | OPRD1 (0.39) | OPRD1OPRK1KCNH2PKMTSHR | |
| SCHEMBL6480972 | 0.76 | OPRD1 (0.55) | OPRD1OPRK1KCNH2TSHRKMT2A | |
| SCHEMBL7039789 | 0.75 | PKM (0.42) | PKMTSHRKMT2ACYP19A1ALDH1A1 | |
| SCHEMBL12365181 | 0.73 | ALDH1A1 (0.43) | KMT2AALDH1A1MAPK1PTPRCMEN1 | |
| SCHEMBL18766393 | 0.73 | ADRA2A (0.35) | TSHRALDH1A1MAPK1MAOB | |
| SCHEMBL8657572 | 0.73 | PKM (0.42) | PKMTSHRKMT2ACYP19A1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220339178-A1 | COMPOSITIONS AND METHODS FOR COGNITIVE PROTECTION OF POLLINATORS AGAINST PESTICIDES | COLEGIO MAYOR DE NUESTRA SENORA DEL ROSARIO (CO) | 2022-10-27 | — | — | US | disclosed |
| CN-114524790-A | C2 alkynyl disubstituted 2H-chromene compound and preparation method thereof | 成都大学 | 2022-05-24 | — | — | CN | disclosed |
| EP-3862029-A1 | STABLE HYDROGEL COMPOSITIONS INCLUDING ADDITIVES | Allergan Industrie, SAS (FR) | 2021-08-11 | — | — | EP | disclosed |
| US-11053471-B1 | Method and preparation for the delivery of selective small molecule phytochemical based and pharmacologically active media through a cell membrane to enhance food groups for health protection and benefits | SAHA ANUJ K (US) | 2021-07-06 | — | — | US | disclosed |
| WO-2021122481-A1 | COMPOSITION COMPRISING A NATURAL DYE AND A FATTY AMINE | L'OREAL (FR) | 2021-06-24 | — | — | WO | disclosed |
| EP-3511028-B1 | STABLE HYDROGEL COMPOSITIONS INCLUDING ADDITIVES | ALLERGAN IND SAS (FR) | 2021-04-07 | — | — | EP | disclosed |
| WO-2021046388-A1 | COMPOSITIONS AND METHODS FOR COGNITIVE PROTECTION OF POLLINATORS AGAINST PESTICIDES | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2021-03-11 | — | — | WO | disclosed |
| US-10918993-B1 | Phipps indoor air filter (PIAF) for capturing and destroying pathogenic viruses like COVID 19 | SAHA ANUJ K (US) | 2021-02-16 | — | — | US | disclosed |
| US-20200330358-A1 | STABLE HYDROGEL COMPOSITIONS INCLUDING ADDITIVES | ALLERGAN INDUSTRIE, SAS (FR) | 2020-10-22 | — | — | US | disclosed |
| US-10806767-B1 | Method and preparation for the delivery of selective small molecule phytochemical based and pharmacologically active media through a cell membrane to enhance food groups for health protection and benefits | SAHA ANUJ K (US) | 2020-10-20 | — | — | US | disclosed |
| US-7064543-B2 | Method of verifying the synthesis of organic molecules using nuclear magnetic resonance spectroscopy | BRUKER BIOSPIN GMBH (DE) | 2006-06-20 | — | — | US | disclosed |
| US-20040096905-A1 | Using spectrum analysis to monitor and evaluate production of compounds within a library of organic compounds produced by combinatorial chemistry; high throughput assay | BRUKER ANALYTIK GMBH (DE) | 2004-05-20 | — | — | US | disclosed |
| US-6596758-B1 | Treatment of dislipidaemias, atherosclerosis and diabetes, to pharmaceutical compositions comprising them and to processes allowing the preparation of these compounds. | MERCK PATENT GMBH (DE) | 2003-07-22 | — | — | US | disclosed |
| EP-1140893-B1 | BENZOPYRANS AND BENZOXEPINES, PHARMACEUTICAL COMPOSITIONS COMPRISING THEM AND PREPARATION PROCESS | MERCK PATENT GMBH (DE) | 2003-03-05 | — | — | EP | disclosed |
| US-6509362-B2 | Cholesteryl acyl transferase (ACAT) inhibitors; treatment of hyperlipidaemia and atherosclerosis. | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 2003-01-21 | — | — | US | disclosed |
| US-20020068739-A1 | New N-phenylamide and N-pyridylamide derivatives, method of preparing them and pharmaceutical compositions containing them | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2002-06-06 | — | — | US | disclosed |
| US-6339097-B1 | FOR THERAPY OF HYPERLIPIDAEMIA AND ATHEROSCLEROSIS; CHOLESTERYL ACYL TRANSFERASE (ACAT) INHIBITORS | MERCK PATENT GMBH (DE) | 2002-01-15 | — | — | US | disclosed |
| US-20020001816-A1 | Method of verifying the synthesis of organic molecules using nuclear magnetic resonance spectroscopy | BRUKER ANALYTIK GMBH (DE) | 2002-01-03 | — | — | US | disclosed |
| EP-1140893-A1 | BENZOPYRANS AND BENZOXEPINES, PHARMACEUTICAL COMPOSITIONS COMPRISING THEM AND PREPARATION PROCESS | MERCK PATENT GmbH (DE) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000039113-A1 | BENZOPYRANS AND BENZOXEPINES, PHARMACEUTICAL COMPOSITIONS COMPRISING THEM AND PREPARATION PROCESS | MERCK PATENT GMBH (DE) | 2000-07-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020068739-A1 | New N-phenylamide and N-pyridylamide derivatives, method of preparing them and pharmaceutical compositions containing them | ACAT2, LCAT, ACAT1 | OPRD1 2599/4885OPRK1 3151/4885KCNH2 2899/4885 |
| US-20220339178-A1 | COMPOSITIONS AND METHODS FOR COGNITIVE PROTECTION OF POLLINATORS AGAINST PESTICIDES | ACHE, BCHE, GAP43 | OPRD1 989/4885OPRK1 741/4885KCNH2 607/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.