Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | PARG | Q86W56 | 1/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13628854 | 0.83 | MAPT (0.36) | MAPTTP53ALDH1A1TSHRHSD17B10 | |
| SCHEMBL13628859 | 0.82 | PTGS2 (0.45) | TP53PTGS2TBXA2R | |
| SCHEMBL13628849 | 0.79 | GAA (0.36) | PARGLMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL13628847 | 0.78 | CYP11B2 (0.43) | MAPTPTGS2NPSR1 | |
| SCHEMBL13628851 | 0.78 | PTGS2 (0.36) | TP53PTGS2ALDH1A1TSHRMEN1 | |
| SCHEMBL13628862 | 0.78 | CYP1A2 (0.36) | MAPTTP53ALDH1A1TSHRHSD17B10 | |
| SCHEMBL2928345 | 0.78 | PTGS2 (0.56) | MAPTTP53PTGS2ALDH1A1TSHR | |
| SCHEMBL13628860 | 0.78 | PTGS2 (0.46) | MAPTTP53PTGS2LMNATBXA2R | |
| SCHEMBL13628853 | 0.77 | PTGS2 (0.37) | MAPTPTGS2ALDH1A1TSHRKMT2A | |
| SCHEMBL13628850 | 0.77 | PTGS2 (0.36) | MAPTPTGS2TSHRKMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7612070-B2 | Heterocyclic compounds as antiinflammatory agents and cyclooxygenase inhibitors | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2009-11-03 | — | — | US | disclosed |