Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.34 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.33 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ACLY | P53396 | 4/20 | 0.33 |
| ▸ | PARG | Q86W56 | 1/20 | 0.32 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.32 |
| ▸ | TUBB | P07437 | 1/20 | 0.32 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.32 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.32 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.32 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.32 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.32 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.32 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.32 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.32 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2925372 | 0.83 | ALDH3A1 (0.38) | GAAHTTL3MBTL1ALDH3A1NOD1 | |
| SCHEMBL13628821 | 0.79 | MAPT (0.37) | LMNAPARGCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL2927942 | 0.77 | HTR6 (0.40) | LMNAACLYHTR6SMN1; SMN2 | |
| SCHEMBL2928861 | 0.74 | CA12 (0.42) | LMNAACLY | |
| SCHEMBL2928345 | 0.67 | PTGS2 (0.56) | PARG | |
| SCHEMBL13628854 | 0.66 | MAPT (0.36) | LMNAPARGCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL13628859 | 0.64 | PTGS2 (0.45) | ACLY | |
| SCHEMBL13628862 | 0.62 | CYP1A2 (0.36) | LMNACYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL13628847 | 0.61 | CYP11B2 (0.43) | ACLYPKM | |
| SCHEMBL17674262 | 0.59 | NTRK1 (0.50) | L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7612070-B2 | Heterocyclic compounds as antiinflammatory agents and cyclooxygenase inhibitors | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2009-11-03 | — | — | US | disclosed |