Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.33 |
| ▸ | GBA1 | P04062 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13224109 | 0.93 | LMNA (0.39) | LMNAPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL11991401 | 0.85 | SORT1 (0.32) | — | |
| SCHEMBL18723033 | 0.73 | ACE2 (0.35) | LMNA | |
| SCHEMBL2608932 | 0.69 | — | — | |
| SCHEMBL13223702 | 0.69 | PSEN1 (0.35) | LMNAPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL1890420 | 0.67 | — | — | |
| SCHEMBL13741693 | 0.67 | EGLN3 (0.46) | LMNA | |
| SCHEMBL12811809 | 0.67 | ALDH1A1 (0.36) | — | |
| SCHEMBL16589325 | 0.67 | LMNA (0.35) | LMNAGBA1 | |
| SCHEMBL441503 | 0.66 | TBXAS1 (0.63) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9918473-B2 | Use of aryl carbamates in agriculture and other plant-related areas | North Carolian State University (US) | 2018-03-20 | — | — | US | disclosed |
| US-20160353739-A1 | USE OF ARYL CARBAMATES IN AGRICULTURE AND OTHER PLANT-RELATED AREAS | UNIV NORTH CAROLINA STATE (US) | 2016-12-08 | — | — | US | disclosed |
| US-9439436-B2 | Use of aryl carbamates in agriculture and other plant-related areas | NORTH CAROLINA STATE UNIVERSITY (US) | 2016-09-13 | — | — | US | disclosed |
| US-20150327552-A1 | USE OF ARYL CARBAMATES IN AGRICULTURE AND OTHER PLANT-RELATED AREAS | UNIV NORTH CAROLINA STATE (US) | 2015-11-19 | — | — | US | disclosed |
| US-9125408-B2 | Use of aryl carbamates in agriculture and other plant-related areas | NORTH CAROLINA STATE UNIVERSITY (US) | 2015-09-08 | — | — | US | disclosed |
| US-8884022-B2 | Inhibition of bacterial biofilms with aryl carbamates | NORTH CAROLINA STATE UNIVERSITY (US) | 2014-11-11 | — | — | US | disclosed |
| US-20130172187-A1 | USE OF ARYL CARBAMATES IN AGRICULTURE AND OTHER PLANT-RELATED AREAS | NORTH CAROLINA STATE UNIVERSITY | 2013-07-04 | — | — | US | disclosed |
| US-20130123225-A1 | INHIBITION OF BACTERIAL BIOFILMS WITH ARYL CARBAMATES | NORTH CAROLINA STATE UNIVERSITY | 2013-05-16 | — | — | US | disclosed |
| US-20090274650-A1 | INHIBITORS OF ASPARTYL PROTEASE | VERTEX PHARMACEUTICALS INCORPORATED | 2009-11-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130172187-A1 | USE OF ARYL CARBAMATES IN AGRICULTURE AND OTHER PLANT-RELATED AREAS | CTRC, ACE, DDT | LMNA 4641/4885PSEN1 3191/4885PSEN2 4002/4885 |
| US-20160353739-A1 | USE OF ARYL CARBAMATES IN AGRICULTURE AND OTHER PLANT-RELATED AREAS | CTRC, ACE, DDT | LMNA 4641/4885PSEN1 3191/4885PSEN2 4002/4885 |
| US-20130123225-A1 | INHIBITION OF BACTERIAL BIOFILMS WITH ARYL CARBAMATES | PGLS, BLVRB, AADAC | LMNA 4530/4885PSEN1 4762/4885PSEN2 4774/4885 |
| US-20150327552-A1 | USE OF ARYL CARBAMATES IN AGRICULTURE AND OTHER PLANT-RELATED AREAS | CTRC, ACE, DDT | LMNA 4641/4885PSEN1 3191/4885PSEN2 4002/4885 |
| US-20090274650-A1 | INHIBITORS OF ASPARTYL PROTEASE | SPINT2, DNPEP, PRSS1 | LMNA 4130/4885PSEN1 314/4885PSEN2 490/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.