SCHEMBL441503

SCHEMBL441503

CC(C)CCCn1ccnc1

nearest known ligand 0.63

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TBXAS1 P24557 13/20 0.63
CYP19A1 P11511 2/20 0.57
PRKCI P41743 1/20 0.51
QPCT Q16769 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL441071 0.94 TBXAS1 (0.67) TBXAS1CYP19A1PRKCIQPCT
SCHEMBL1918271 0.92 TBXAS1 (0.70) TBXAS1CYP19A1
SCHEMBL11216310 0.92 TBXAS1 (0.70) TBXAS1CYP19A1
SCHEMBL1917309 0.92 TBXAS1 (0.70) TBXAS1CYP19A1
SCHEMBL27225880 0.92 TBXAS1 (0.70) TBXAS1CYP19A1
SCHEMBL8251694 0.92 TBXAS1 (0.70) TBXAS1CYP19A1
SCHEMBL439530 0.88 TBXAS1 (0.56) TBXAS1CYP19A1PRKCIQPCT
Hydrochloric Acid SCHEMBL18318545 0.86 TBXAS1 (0.54) TBXAS1CYP19A1PRKCIQPCT
Bromide SCHEMBL29287563 0.86 TBXAS1 (0.54) TBXAS1CYP19A1PRKCIQPCT
Water SCHEMBL28290667 0.86 TBXAS1 (0.54) TBXAS1CYP19A1PRKCIQPCT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 134 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240238473-A1 RECOMBINANT NUCLEIC ACID MOLECULES AND THEIR USE IN WOUND HEALING PRESIDENT AND FELLOWS OF HARVARD COLLEGE 2024-07-18 US disclosed
WO-2024098053-A1 POLYMER-NUCLEIC ACID NANOPARTICLES FOR GENE EDITING THE JOHNS HOPKINS UNIVERSITY (US) 2024-05-10 WO disclosed
US-11771715-B2 Circular RNA compositions and methods ORNA THERAPEUTICS, INC. (US) 2023-10-03 US disclosed
US-11771715-B2 Circular RNA compositions and methods ORNA THERAPEUTICS, INC. (US) 2023-10-03 US disclosed
US-11766449-B2 Circular RNA compositions and methods ORNA THERAPEUTICS, INC. (US) 2023-09-26 US disclosed
US-11766449-B2 Circular RNA compositions and methods ORNA THERAPEUTICS, INC. (US) 2023-09-26 US disclosed
US-20230293706-A1 Multicomponent Delivery Systems for Polyanionic Cargo Compound Delivery MEDICI THERAPEUTICS, INC. 2023-09-21 US disclosed
US-20230293706-A1 Multicomponent Delivery Systems for Polyanionic Cargo Compound Delivery MEDICI THERAPEUTICS, INC. 2023-09-21 US disclosed
US-20230226096-A1 CIRCULAR RNA COMPOSITIONS AND METHODS ORNA THERAPEUTICS, INC. 2023-07-20 US disclosed
US-20230226096-A1 CIRCULAR RNA COMPOSITIONS AND METHODS ORNA THERAPEUTICS, INC. 2023-07-20 US disclosed
US-7276505-B2 Immunomodulating heterocyclic compounds MEDIGENE LIMITED (GB) 2007-10-02 US disclosed
US-20070208049-A1 Gonadotropin-releasing hormone receptor antagonists and methods relating thereto NEUROCRINE BIOSCIENCES, INC. (US) 2007-09-06 US disclosed
US-20070208049-A1 Gonadotropin-releasing hormone receptor antagonists and methods relating thereto NEUROCRINE BIOSCIENCES, INC. (US) 2007-09-06 US disclosed
US-20070203183-A1 Diaryl piperidines as CB1 modulators SCHERING CORPORATION 2007-08-30 US disclosed
US-20070203183-A1 Diaryl piperidines as CB1 modulators SCHERING CORPORATION 2007-08-30 US disclosed
US-20070043051-A1 Methods and compositions of novel triazine compounds TIMMER RICHARD T 2007-02-22 US disclosed
US-7179815-B2 Gonadotropin-releasing hormone receptor antagonists and methods relating thereto NEUROCRINE BIOSCIENCES, INC. (US) 2007-02-20 US disclosed
US-7179815-B2 Gonadotropin-releasing hormone receptor antagonists and methods relating thereto NEUROCRINE BIOSCIENCES, INC. (US) 2007-02-20 US disclosed
US-20070021428-A1 Immunomodulating heterocyclic compounds AVIDEX LIMITED (GB) 2007-01-25 US disclosed
CN-1894174-A Method for isolating acids from chemical reaction mixtures by using 1-alkylimidazoles BASF AG (DE) 2007-01-10 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230293706-A1 Multicomponent Delivery Systems for Polyanionic Cargo Compound Delivery MTREX, EXOSC5, KPNA6 TBXAS1 2281/4885CYP19A1 4669/4885PRKCI 2161/4885
US-20070203183-A1 Diaryl piperidines as CB1 modulators CNR1, CNR2, GPR119 TBXAS1 1560/4885CYP19A1 1708/4885PRKCI 2480/4885
US-11771715-B2 Circular RNA compositions and methods RTCB, HNRNPA1, HNRNPAB TBXAS1 2858/4885CYP19A1 2822/4885PRKCI 1015/4885
US-20070043051-A1 Methods and compositions of novel triazine compounds AREG, TGFB1, PTGIS TBXAS1 100/4885CYP19A1 4658/4885PRKCI 1485/4885
US-20240238473-A1 RECOMBINANT NUCLEIC ACID MOLECULES AND THEIR USE IN WOUND HEALING CHI3L2, CHI3L1, FGF2 TBXAS1 3816/4885CYP19A1 4746/4885PRKCI 3364/4885
US-20230226096-A1 CIRCULAR RNA COMPOSITIONS AND METHODS RTCB, HNRNPA1, HNRNPAB TBXAS1 2858/4885CYP19A1 2822/4885PRKCI 1015/4885
US-20070021428-A1 Immunomodulating heterocyclic compounds CD40, CD40LG, NGFR TBXAS1 3407/4885CYP19A1 1964/4885PRKCI 3163/4885
US-20070208049-A1 Gonadotropin-releasing hormone receptor antagonists and methods relating thereto GNRHR, GHRHR, LHCGR TBXAS1 2299/4885CYP19A1 35/4885PRKCI 3788/4885
US-11766449-B2 Circular RNA compositions and methods RTCB, RNGTT, HNRNPAB TBXAS1 2889/4885CYP19A1 3057/4885PRKCI 848/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.