Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UBE2M | P61081 | 2/20 | 0.41 |
| ▸ | DCUN1D1 | Q96GG9 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | CCR4 | P51679 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | FPR2 | P25090 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | G6PD | P11413 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13664728 | 0.74 | BACE1 (0.43) | UBE2MDCUN1D1MEN1KMT2AGAA | |
| SCHEMBL13664869 | 0.73 | SIGMAR1 (0.46) | MEN1KMT2ATDP1KCNH2EPHX2 | |
| SCHEMBL8716574 | 0.72 | SIGMAR1 (0.52) | MEN1KMT2AGAATDP1KCNH2 | |
| SCHEMBL13664860 | 0.71 | MMP8 (0.41) | MEN1KMT2AKCNH2EPHX2CCR4 | |
| SCHEMBL8140522 | 0.68 | HPGD (0.50) | UBE2MDCUN1D1MEN1KMT2AGAA | |
| SCHEMBL24326164 | 0.68 | L3MBTL1 (0.45) | MEN1KMT2AHTTSIGMAR1ATM | |
| SCHEMBL1650495 | 0.67 | CA2 (0.47) | — | |
| SCHEMBL13664802 | 0.66 | MEN1 (0.50) | MEN1KMT2AHTTFPR2 | |
| SCHEMBL123966 | 0.65 | CA2 (0.45) | — | |
| SCHEMBL5007883 | 0.65 | CCR4 (0.49) | MEN1KMT2AGAATDP1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009119528-A1 | HETEROCYCLIC COMPOUND | 武田薬品工業株式会社 (JP) | 2009-10-01 | — | — | WO | disclosed |