Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
| ▸ | PGK1 | P00558 | 1/20 | 0.32 |
| ▸ | PGK2 | P07205 | 1/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.31 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.31 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.31 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | APEX1 | P27695 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1366701 | 0.98 | CES2 (0.39) | CES2TSHRNAAAPGK1PGK2 | |
| SCHEMBL1368625 | 0.90 | THRB (0.37) | TSHRPGK1PGK2BTN3A1TDP1 | |
| SCHEMBL21052534 | 0.83 | PRSS1 (0.38) | CES2TSHRNAAAPRSS1PRSS2 | |
| SCHEMBL21052530 | 0.83 | PRSS1 (0.38) | CES2TSHRNAAAPRSS1PRSS2 | |
| SCHEMBL21052531 | 0.83 | PRSS1 (0.38) | CES2TSHRNAAAPRSS1PRSS2 | |
| SCHEMBL1367358 | 0.80 | TSHR (0.56) | TSHRNAAAPGK1PGK2POLB | |
| SCHEMBL11221476 | 0.80 | TSHR (0.46) | CES2TSHRNAAAPRSS1PRSS2 | |
| SCHEMBL11232200 | 0.80 | PRSS1 (0.47) | CES2TSHRNAAAPRSS1PRSS2 | |
| SCHEMBL1366702 | 0.79 | TSHR (0.59) | TSHRNAAAPGK1PGK2POLB | |
| SCHEMBL12895904 | 0.79 | TSHR (0.59) | TSHRNAAAPGK1PGK2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2123246-B1 | ADHESIVE COMPOSITION FOR DENTAL USE | TOKUYAMA DENTAL CORP (JP) | 2021-06-23 | — | — | EP | disclosed |
| EP-2305205-B1 | DENTAL ADHESIVE COMPOSITION | TOKUYAMA DENTAL CORP (JP) | 2018-04-11 | — | — | EP | disclosed |
| US-8796354-B2 | Dental adhesive composition | TOKUYAMA DENTAL CORPORATION (JP) | 2014-08-05 | — | — | US | disclosed |
| US-8546459-B2 | Dental filling/restoration kit | TOKUYAMA DENTAL CORPORATION (JP) | 2013-10-01 | — | — | US | disclosed |
| US-8513327-B2 | Adhesive composition for dental use | TOKUYAMA DENTAL CORPORATION (JP) | 2013-08-20 | — | — | US | disclosed |
| US-20110288195-A1 | DENTAL FILLING/RESTORATION KIT | TOKUYAMA DENTAL CORPORATION (JP) | 2011-11-24 | — | — | US | disclosed |
| US-20110098375-A1 | DENTAL ADHESIVE COMPOSITION | TOKUYAMA DENTAL CORPORATION (JP) | 2011-04-28 | — | — | US | disclosed |
| EP-2305205-A1 | DENTAL ADHESIVE COMPOSITION | Tokuyama Dental Corporation (JP) | 2011-04-06 | — | — | EP | disclosed |
| US-20100317762-A1 | ADHESIVE COMPOSITION FOR DENTAL USE | TOKUYAMA DENTAL CORPORATION | 2010-12-16 | — | — | US | disclosed |
| EP-2123246-A1 | ADHESIVE COMPOSITION FOR DENTAL USE | Tokuyama Dental Corporation (JP) | 2009-11-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100317762-A1 | ADHESIVE COMPOSITION FOR DENTAL USE | ITGA1, VMA21, ITGA6 | CES2 4472/4885TSHR 1077/4885NAAA 626/4885 |
| US-20110098375-A1 | DENTAL ADHESIVE COMPOSITION | CAD, CDH1, ITGA4 | CES2 4130/4885TSHR 2496/4885NAAA 2122/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.