SCHEMBL1366701

SCHEMBL1366701

C=C(C)COCCCCCCOC(=O)CP(=O)(O)O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 2/20 0.39
TSHR P16473 3/20 0.37
NAAA Q02083 1/20 0.36
PRSS1 P07477 1/20 0.33
PRSS2 P07478 1/20 0.33
PRSS3 P35030 1/20 0.33
POLB P06746 1/20 0.32
APEX1 P27695 1/20 0.32
HTT P42858 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
RAD52 P43351 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
PGK1 P00558 1/20 0.31
PGK2 P07205 1/20 0.31
FAAH O00519 1/20 0.31
ALDH1A1 P00352 1/20 0.31
CYP3A4 P08684 1/20 0.31
P2RY10 O00398 3/20 0.30
HTR2C P28335 1/20 0.30
GPR34 Q9UPC5 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1367356 0.98 CES2 (0.36) CES2TSHRNAAAPRSS1PRSS2
SCHEMBL1368625 0.89 THRB (0.37) TSHRTDP1PGK1PGK2ALDH1A1
SCHEMBL21052530 0.85 PRSS1 (0.38) CES2TSHRNAAAPRSS1PRSS2
SCHEMBL21052531 0.85 PRSS1 (0.38) CES2TSHRNAAAPRSS1PRSS2
SCHEMBL21052534 0.85 PRSS1 (0.38) CES2TSHRNAAAPRSS1PRSS2
SCHEMBL11221476 0.82 TSHR (0.46) CES2TSHRNAAAPRSS1PRSS2
SCHEMBL12895911 0.81 TSHR (0.59) TSHRNAAAPOLBAPEX1HTT
SCHEMBL12895904 0.81 TSHR (0.59) TSHRNAAAPOLBAPEX1HTT
SCHEMBL1366702 0.81 TSHR (0.59) TSHRNAAAPOLBAPEX1HTT
SCHEMBL12895909 0.81 TSHR (0.59) TSHRNAAAPOLBAPEX1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8449869-B2 Artificial nail composition having improved adhesion property KABUSHIKI KAISHA SHOFU (JP) 2013-05-28 US claimed
EP-4717249-A1 DENTAL COMPOSITION Shofu Inc. (JP) 2026-04-01 EP disclosed
US-20260083642-A1 DENTAL COMPOSITION SHOFU INC (JP) 2026-03-26 US disclosed
US-20260060900-A1 DENTAL COMPOSITE RESIN KIT SHOFU INC. (JP) 2026-03-05 US disclosed
US-RE50759-E1 Dental composite material having stable pasty property SHOFU INC. (JP) 2026-01-27 US disclosed
US-20250381101-A1 HIGHLY FLOWABLE DENTAL CURABLE COMPOSITION SHOFU INC. (JP) 2025-12-18 US disclosed
EP-4437049-B1 PRIMERS FOR ENERGY-CURABLE INKS AND COATINGS ON METALLIZED SUBSTRATES SUN CHEMICAL CORP (US) 2025-07-09 EP disclosed
US-20250136819-A1 PRIMERS FOR ENERGY-CURABLE INKS AND COATINGS ON METALLIZED SUBSTRATES SUN CHEMICAL CORPORATION (US) 2025-05-01 US disclosed
US-20250064686-A1 DENTAL CURABLE COMPOSITION CONTAINING ULTRAVIOLET ABSORBER SHOFU INC (JP) 2025-02-27 US disclosed
EP-4473954-A1 DENTAL CURABLE COMPOSITION CONTAINING ULTRAVIOLET ABSORBER Shofu Inc. (JP) 2024-12-11 EP disclosed
US-8546459-B2 Dental filling/restoration kit TOKUYAMA DENTAL CORPORATION (JP) 2013-10-01 US disclosed
US-8513327-B2 Adhesive composition for dental use TOKUYAMA DENTAL CORPORATION (JP) 2013-08-20 US disclosed
US-8449869-B2 Artificial nail composition having improved adhesion property KABUSHIKI KAISHA SHOFU (JP) 2013-05-28 US disclosed
CN-102300545-A Dental filling repair kit 2011-12-28 CN disclosed
US-20110288195-A1 DENTAL FILLING/RESTORATION KIT TOKUYAMA DENTAL CORPORATION (JP) 2011-11-24 US disclosed
US-20110098375-A1 DENTAL ADHESIVE COMPOSITION TOKUYAMA DENTAL CORPORATION (JP) 2011-04-28 US disclosed
EP-2305205-A1 DENTAL ADHESIVE COMPOSITION Tokuyama Dental Corporation (JP) 2011-04-06 EP disclosed
US-20100317762-A1 ADHESIVE COMPOSITION FOR DENTAL USE TOKUYAMA DENTAL CORPORATION 2010-12-16 US disclosed
US-20100055057-A1 Artificial nail composition having improved adhesion property KABUSHIKI KAISHA SHOFU (JP) 2010-03-04 US disclosed
EP-2123246-A1 ADHESIVE COMPOSITION FOR DENTAL USE Tokuyama Dental Corporation (JP) 2009-11-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260060900-A1 DENTAL COMPOSITE RESIN KIT BOLA2; BOLA2B, LBR, COL2A1 CES2 578/4885TSHR 3276/4885NAAA 1250/4885
US-20250381101-A1 HIGHLY FLOWABLE DENTAL CURABLE COMPOSITION RCC1, H1-0, H1-3 CES2 1890/4885TSHR 2062/4885NAAA 4061/4885
US-20250064686-A1 DENTAL CURABLE COMPOSITION CONTAINING ULTRAVIOLET ABSORBER ERCC1, DSC1, CRYAA CES2 2483/4885TSHR 4039/4885NAAA 2543/4885
US-20100055057-A1 Artificial nail composition having improved adhesion property POLR1C, NACA, PIK3C3 CES2 4864/4885TSHR 3831/4885NAAA 1249/4885
US-20100317762-A1 ADHESIVE COMPOSITION FOR DENTAL USE ITGA1, VMA21, ITGA6 CES2 4472/4885TSHR 1077/4885NAAA 626/4885
US-20260083642-A1 DENTAL COMPOSITION TAS2R42, COL2A1, TAS2R1 CES2 416/4885TSHR 1588/4885NAAA 1604/4885
US-20110098375-A1 DENTAL ADHESIVE COMPOSITION CAD, CDH1, ITGA4 CES2 4130/4885TSHR 2496/4885NAAA 2122/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.