Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | KLK7 | P49862 | 1/20 | 0.47 |
| ▸ | MMP13 | P45452 | 1/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.42 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.42 |
| ▸ | PIP4K2B | P78356 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13680461 | 0.83 | SMN1; SMN2 (0.60) | ALDH1A1KMT2AMAPTKDM4EMEN1 | |
| SCHEMBL13680488 | 0.82 | KIF11 (0.59) | ALDH1A1KMT2AMAPTKDM4EMEN1 | |
| SCHEMBL13680486 | 0.81 | MAPT (0.52) | ALDH1A1KMT2AMAPTKDM4EMEN1 | |
| SCHEMBL13680492 | 0.79 | TSHR (0.51) | ALDH1A1KMT2AMAPTKDM4EMEN1 | |
| SCHEMBL14699695 | 0.77 | APP (0.44) | ALDH1A1KMT2AMAPTKDM4EMEN1 | |
| SCHEMBL13680504 | 0.77 | PLK1 (0.50) | ALDH1A1KMT2AMAPTKDM4EMEN1 | |
| SCHEMBL10155599 | 0.76 | ALDH1A1 (0.78) | ALDH1A1KMT2AMAPTKDM4ENPC1 | |
| SCHEMBL13680490 | 0.76 | PSMB8 (0.54) | ALDH1A1KMT2AMAPTKDM4EMEN1 | |
| SCHEMBL13680705 | 0.75 | ALDH1A1 (0.48) | ALDH1A1KMT2AMAPTKDM4EMEN1 | |
| SCHEMBL13680873 | 0.75 | ALDH1A1 (0.43) | ALDH1A1KMT2AMAPTKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |