Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 9/20 | 0.41 |
| ▸ | TRPV3 | Q8NET8 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.31 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.31 |
| ▸ | TEK | Q02763 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 2/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13680849 | 0.84 | SCN9A (0.43) | SCN9A | |
| SCHEMBL13680824 | 0.84 | SUCNR1 (0.44) | SCN9ATRPV3CYP1A2ALDH1A1SUCNR1 | |
| SCHEMBL13680850 | 0.81 | TRPV3 (0.53) | SCN9ATRPV3 | |
| SCHEMBL13680823 | 0.80 | TRPV3 (0.34) | TRPV3 | |
| SCHEMBL13680846 | 0.79 | MAPT (0.40) | SCN9ATRPV3PDE10A | |
| SCHEMBL13680956 | 0.79 | SHMT2 (0.40) | ALDH1A1POLBL3MBTL1 | |
| SCHEMBL13680798 | 0.78 | CYP1A2 (0.38) | CYP1A2CYP3A4CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL13680847 | 0.77 | PDE10A (0.43) | SCN9ATRPV3IRAK4PDE10A | |
| SCHEMBL13680818 | 0.77 | TRPV3 (0.52) | SCN9ATRPV3PDE10A | |
| SCHEMBL13680477 | 0.75 | CYP2A6 (0.46) | SCN9ACYP1A2CYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |