Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.38 |
| ▸ | RELA | Q04206 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13680838 | 0.88 | SCN9A (0.42) | RAB9ANPC1KMT2AMEN1SCN9A | |
| SCHEMBL13680839 | 0.88 | ALDH1A1 (0.45) | RAB9ANPC1KMT2ALMNAGAA | |
| SCHEMBL13680842 | 0.88 | RAB9A (0.45) | RAB9ANPC1KMT2ALMNAGAA | |
| SCHEMBL13681339 | 0.86 | SCN9A (0.38) | RAB9ANPC1KMT2ASCN9AMAPT | |
| SCHEMBL13680815 | 0.85 | PDE10A (0.46) | RAB9ANPC1KMT2AMEN1LMNA | |
| SCHEMBL13680825 | 0.82 | MAPT (0.41) | KMT2ALMNASCN9AHSD17B10MAPT | |
| SCHEMBL13680828 | 0.81 | ALDH1A1 (0.42) | RAB9ANPC1KMT2AMEN1LMNA | |
| SCHEMBL13680834 | 0.80 | PDE10A (0.39) | RAB9AKMT2AMEN1HSD17B10MAPT | |
| SCHEMBL13680830 | 0.80 | RARA (0.44) | RAB9ANPC1GAANFKB1NFKB2 | |
| SCHEMBL13680827 | 0.79 | KMT2A (0.50) | RAB9ANPC1KMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |