Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 14/20 | 0.42 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13680840 | 0.88 | RAB9A (0.41) | SCN9AKMT2AMEN1NPC1MAPT | |
| SCHEMBL13681339 | 0.88 | SCN9A (0.38) | SCN9AKMT2APARP1NPC1MAPT | |
| SCHEMBL13680842 | 0.84 | RAB9A (0.45) | SCN9AKMT2ANPC1MAPTNFKB1 | |
| SCHEMBL13680839 | 0.84 | ALDH1A1 (0.45) | SCN9AKMT2ANPC1MAPTNFKB1 | |
| SCHEMBL13680835 | 0.83 | MAP4K4 (0.42) | SCN9AAOC3NPC1RAB9A | |
| SCHEMBL27747193 | 0.81 | SCN9A (0.47) | SCN9AKIF11KMT2AMEN1PARP1 | |
| SCHEMBL13680815 | 0.81 | PDE10A (0.46) | SCN9AKMT2AMEN1PARP1NPC1 | |
| SCHEMBL13680830 | 0.79 | RARA (0.44) | NPC1NFKB1RAB9ANFKB2RELA | |
| SCHEMBL13680825 | 0.79 | MAPT (0.41) | SCN9AKMT2AMAPTSMN1; SMN2 | |
| SCHEMBL13680824 | 0.78 | SUCNR1 (0.44) | SCN9ANPC1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |