Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 2/20 | 0.40 |
| ▸ | PPARA | Q07869 | 2/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | TP53 | P04637 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13680959 | 0.86 | CYP19A1 (0.53) | PPARDPPARACYP19A1ALDH1A1KDM4E | |
| SCHEMBL13680957 | 0.83 | KDM4E (0.50) | ALDH1A1KDM4EHPGDGAAMAPT | |
| SCHEMBL13680956 | 0.81 | SHMT2 (0.40) | PPARDPPARACYP19A1ALDH1A1KDM4E | |
| SCHEMBL13680955 | 0.79 | GAA (0.42) | ALDH1A1KDM4EHPGDGAAMAPT | |
| SCHEMBL13680949 | 0.79 | HPGDS (0.43) | ALDH1A1KDM4EHPGDGAAMAPT | |
| SCHEMBL13681036 | 0.78 | KMT2A (0.37) | ALDH1A1KDM4EHPGDGAAMAPT | |
| SCHEMBL13680954 | 0.77 | KDM4E (0.40) | ALDH1A1KDM4EGAAMAPTTP53 | |
| SCHEMBL13680932 | 0.77 | KMT2A (0.47) | ALDH1A1KDM4EHPGDMAPTTP53 | |
| SCHEMBL13680953 | 0.77 | LMNA (0.41) | ALDH1A1KDM4EHPGDGAAMAPT | |
| SCHEMBL13681055 | 0.76 | KDM4E (0.46) | ALDH1A1KDM4EHPGDGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |