Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GUSB | P08236 | 2/20 | 1.00 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.81 |
| ▸ | MAPT | P10636 | 4/20 | 0.77 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.77 |
| ▸ | MEN1 | O00255 | 3/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.77 |
| ▸ | HPGD | P15428 | 3/20 | 0.77 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.77 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.77 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.77 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.77 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.77 |
| ▸ | THRB | P10828 | 1/20 | 0.77 |
| ▸ | MAOB | P27338 | 3/20 | 0.72 |
| ▸ | AR | P10275 | 1/20 | 0.72 |
| ▸ | BCHE | P06276 | 1/20 | 0.70 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.70 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL127853 | 1.00 | GUSB (1.00) | GUSBCHRNA7MAPTKDM4EMEN1 | |
| Chalcone SCHEMBL1269454 | 0.94 | GUSB (0.88) | GUSBCHRNA7MAPTKDM4EMEN1 | |
| SCHEMBL634059 | 0.90 | CHRNA7 (1.00) | GUSBCHRNA7MAPTKDM4EMEN1 | |
| SCHEMBL634060 | 0.90 | CHRNA7 (1.00) | GUSBCHRNA7MAPTKDM4EMEN1 | |
| 2',4'-Dihydroxychalcone SCHEMBL25200440 | 0.87 | MAPT (1.00) | GUSBCHRNA7MAPTKDM4EMEN1 | |
| 2',4'-Dihydroxychalcone SCHEMBL1411695 | 0.87 | MAPT (1.00) | GUSBCHRNA7MAPTKDM4EMEN1 | |
| 2',4'-Dihydroxychalcone SCHEMBL127341 | 0.87 | MAPT (1.00) | GUSBCHRNA7MAPTKDM4EMEN1 | |
| SCHEMBL5450213 | 0.85 | GUSB (0.74) | GUSBMAPTMAOBARBCHE | |
| SCHEMBL5450210 | 0.85 | GUSB (0.74) | GUSBMAPTMAOBARBCHE | |
| SCHEMBL4119024 | 0.84 | GUSB (0.72) | GUSBCHRNA7MAPTKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 114 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260014100-A1 | Compositions and Methods for Treating Bleeding and Bleeding Disorders | YEWSAVIN INC (US) | 2026-01-15 | — | — | US | disclosed |
| US-12343317-B2 | Compositions and methods for treating bleeding and bleeding disorders | YewSavin, Inc. (US) | 2025-07-01 | — | — | US | disclosed |
| US-20250136987-A1 | CHANNEL MODULATORS | INFLAMMX THERAPEUTICS, INC. | 2025-05-01 | — | — | US | disclosed |
| EP-4491184-A2 | CHANNEL MODULATORS | Auckland Uniservices Limited (NZ) | 2025-01-15 | — | — | EP | disclosed |
| EP-3183346-B1 | CHANNEL MODULATORS | AUCKLAND UNISERVICES LTD (NZ) | 2024-10-23 | — | — | EP | disclosed |
| US-20240335395-A1 | COMPOSITIONS AND METHODS FOR PREVENTING AND/OR TREATING DISEASE ASSOCIATED WITH IL-23 EXPRESSION | ALLSPIM (FR) | 2024-10-10 | — | — | US | disclosed |
| EP-4429763-A1 | COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS | Yewsavin, Inc. (US) | 2024-09-18 | — | — | EP | disclosed |
| EP-4370107-A1 | COMPOSITIONS AND METHODS FOR PREVENTING AND/OR TREATING DISEASE ASSOCIATED WITH IL-23 EXPRESSION | Allspim (FR) | 2024-05-22 | — | — | EP | disclosed |
| CN-118019528-A | Compositions and methods for preventing and/or treating diseases associated with IL-23 expression | ALLSPIM公司 | 2024-05-10 | — | — | CN | disclosed |
| EP-4228408-A1 | PEST REPELLENTS AND USES THEREOF | Sensorygen, Inc. (US) | 2023-08-23 | — | — | EP | disclosed |
| US-7268115-B2 | Cyclic peptides; three-dimensional structures; screening; anticancer agents; angiogenesis inhibitors; drug delivery | ADHEREX TECHNOLOGIES, INC. (CA) | 2007-09-11 | — | — | US | disclosed |
| WO-2007073518-A9 | COMPOUNDS AND METHODS FOR THIOL-CONTAINING COMPOUND EFFLUX AND CANCER TREATMENT | NAT JEWISH MED & RES CENTER (US) | 2007-08-23 | — | — | WO | disclosed |
| WO-2007073518-A2 | COMPOUNDS AND METHODS FOR THIOL-CONTAINING COMPOUND EFFLUX AND CANCER TREATMENT | NATIONAL JEWISH MEDICAL AND RESEARCH CENTER (US) | 2007-06-28 | — | — | WO | disclosed |
| EP-1625150-B9 | TRIPEPTIDES AND DERIVATIVES THEREOF FOR COSMETIC APPLICATION IN ORDER TO IMPROVE SKIN STRUCTURE | PENTAPHARM AG (CH) | 2007-06-13 | — | — | EP | disclosed |
| EP-1625150-B1 | TRIPEPTIDES AND DERIVATIVES THEREOF FOR COSMETIC APPLICATION IN ORDER TO IMPROVE SKIN STRUCTURE | PENTAPHARM AG (CH) | 2007-01-03 | — | — | EP | disclosed |
| EP-1676512-A2 | Skin treatment articles and methods | Johnson and Johnson Consumer Companies, Inc. (US) | 2006-07-05 | — | — | EP | disclosed |
| US-20060141014-A1 | Skin treatment articles and methods | EKNOIAN MICHAEL W | 2006-06-29 | — | — | US | disclosed |
| US-20060135585-A1 | Compounds and methods for thiol-containing compound efflux and cancer treatment | NATIONAL JEWISH MEDICAL AND RESEARCH CENTER (US) | 2006-06-22 | — | — | US | disclosed |
| US-20040176471-A1 | Novel chalcone derivatives and pharmaceutical compositions comprising the same | KAOHSIUNG MEDICAL UNIVERSITY | 2004-09-09 | — | — | US | disclosed |
| US-6217889-B1 | DISPOSABLE PRODUCT; CLEANING COMPOUNDS | THE PROCTOR & GAMBLE COMPANY | 2001-04-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060135585-A1 | Compounds and methods for thiol-containing compound efflux and cancer treatment | ABCC1, ABCC2, ABCB1 | GUSB 681/4885CHRNA7 4863/4885MAPT 4577/4885 |
| US-20040176471-A1 | Novel chalcone derivatives and pharmaceutical compositions comprising the same | PTGS1, PTGES2, PTGES | GUSB 2479/4885CHRNA7 3981/4885MAPT 1667/4885 |
| US-20260014100-A1 | Compositions and Methods for Treating Bleeding and Bleeding Disorders | SERPINC1, F2, F13B | GUSB 1374/4885CHRNA7 4629/4885MAPT 3297/4885 |
| US-12343317-B2 | Compositions and methods for treating bleeding and bleeding disorders | SERPINC1, SERPINE1, SERPINH1 | GUSB 1171/4885CHRNA7 4806/4885MAPT 3512/4885 |
| US-20060141014-A1 | Skin treatment articles and methods | CUTA, KRT18, DSG1 | GUSB 103/4885CHRNA7 4735/4885MAPT 1594/4885 |
| US-20250136987-A1 | CHANNEL MODULATORS | GJB2, GJA1, P2RX2 | GUSB 4256/4885CHRNA7 198/4885MAPT 2406/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.