Sugi Predict

Sugi Predict / Compounds / SCHEMBL288760

SCHEMBL288760

SCHEMBL288760

CC(C)CCNCC(=O)O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 1/20 0.40
▸ LMNA P02545 1/20 0.40
▸ MAPT P10636 1/20 0.40
▸ PTGS2 P35354 1/20 0.40
▸ TDP1 Q9NUW8 1/20 0.40
▸ GABRP O00591 2/20 0.39
▸ GABRD O14764 2/20 0.39
▸ GABRA1 P14867 2/20 0.39
▸ GABRB1 P18505 2/20 0.39
▸ GABRG2 P18507 2/20 0.39
▸ GABRB3 P28472 2/20 0.39
▸ GABRA5 P31644 2/20 0.39
▸ GABRA3 P34903 2/20 0.39
▸ GABRA2 P47869 2/20 0.39
▸ GABRB2 P47870 2/20 0.39
▸ GABRA4 P48169 2/20 0.39
▸ GABRE P78334 2/20 0.39
▸ GABRA6 Q16445 2/20 0.39
▸ GABRG1 Q8N1C3 2/20 0.39
▸ GABRG3 Q99928 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11932533 0.86 KDM4C (0.44) ALDH1A1LMNAMAPTPTGS2TDP1
SCHEMBL18251527 0.84 GABRP (0.43) LMNAGABRPGABRDGABRA1GABRB1
SCHEMBL22043852 0.84 ALDH1A1 (0.43) ALDH1A1LMNAMAPTPTGS2TDP1
SCHEMBL11414508 0.83 KDM4C (0.50) ALDH1A1LMNAMAPTPTGS2TDP1
SCHEMBL6139538 0.83 KDM4C (0.50) ALDH1A1LMNAMAPTPTGS2TDP1
SCHEMBL7305082 0.83 KDM4C (0.50) ALDH1A1LMNAMAPTPTGS2TDP1
SCHEMBL9094272 0.83 KDM4C (0.50) ALDH1A1LMNAMAPTPTGS2TDP1
Bromide SCHEMBL11779655 0.81 KDM4C (0.49) ALDH1A1LMNAMAPTPTGS2TDP1
Water SCHEMBL11587520 0.81 KDM4C (0.49) ALDH1A1LMNAMAPTPTGS2TDP1
SCHEMBL13815320 0.81 ALDH1A1 (0.40) ALDH1A1LMNATDP1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 115 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3328877-B1 PEPTOID THE UNIV OF DURHAM (GB) 2022-08-24 — — EP claimed
CN-108358797-A A kind of synthetic method of alkyl glycine 南京农业大学 2018-08-03 — — CN claimed
US-20180201647-A1 Peptoid THE UNIVERSITY OF DURHAM (GB) 2018-07-19 — — US claimed
US-10017481-B2 Conformationally constrained, fully synthetic macrocyclic compounds POLYPHOR AG (CH) 2018-07-10 — — US claimed
EP-2836485-B1 CONFORMATIONALLY CONSTRAINED, FULLY SYNTHETIC MACROCYCLIC COMPOUNDS POLYPHOR AG (CH) 2018-01-10 — — EP claimed
US-9695191-B2 Conformationally constrained, fully synthetic macrocyclic compounds POLYPHOR AG (CH) 2017-07-04 — — US claimed
EP-2499148-B1 CONFORMATIONALLY CONSTRAINED, FULLY SYNTHETIC MACROCYCLIC COMPOUNDS POLYPHOR AG (CH) 2017-01-18 — — EP claimed
US-9512139-B2 Conformationally constrained, fully synthetic macrocyclic compounds POLYPHOR AG (CH) 2016-12-06 — — US claimed
US-20150051183-A1 CONFORMATIONALLY CONSTRAINED, FULLY SYNTHETIC MACROCYCLIC COMPOUNDS POLYPHOR AG (CH) 2015-02-19 — — US claimed
EP-2836485-A1 CONFORMATIONALLY CONSTRAINED, FULLY SYNTHETIC MACROCYCLIC COMPOUNDS Polyphor Ag (CH) 2015-02-18 — — EP claimed
EP-2462147-B1 CONFORMATIONALLY CONSTRAINED, FULLY SYNTHETIC MACROCYCLIC COMPOUNDS POLYPHOR AG (CH) 2014-11-12 — — EP claimed
WO-2013139697-A1 CONFORMATIONALLY CONSTRAINED, FULLY SYNTHETIC MACROCYCLIC COMPOUNDS POLYPHOR AG (CH) 2013-09-26 — — WO claimed
US-20120270881-A1 CONFORMATIONALLY CONSTRAINED, FULLY SYNTHETIC MACROCYCLIC COMPOUNDS POLYPHOR AG (CH) 2012-10-25 — — US claimed
EP-2499148-A2 CONFORMATIONALLY CONSTRAINED, FULLY SYNTHETIC MACROCYCLIC COMPOUNDS Polyphor Ag (CH) 2012-09-19 — — EP claimed
US-20120202821-A1 CONFORMATIONALLY CONSTRAINED, FULLY SYNTHETIC MACROCYCLIC COMPOUNDS POLYPHOR AG (CH) 2012-08-09 — — US claimed
WO-2011014973-A2 CONFORMATIONALLY CONSTRAINED, FULLY SYNTHETIC MACROCYCLIC COMPOUNDS POLYPHOR AG (CH) 2011-02-10 — — WO claimed
EP-4724459-A1 PEPTIDE COMPOSITIONS TARGETING GLYPICAN-3 AND USES THEREOF Peptidream Inc (JP) 2026-04-15 — — EP disclosed
US-20260098061-A1 EPHA2-BINDING PENDING PEPTIDE AND COMPOSITION COMPRISING SAME PEPTIDREAM INC (JP) 2026-04-09 — — US disclosed
EP-0509080-A1 INHIBITORS AND SUBSTRATES OF THROMBIN ELLERMAN PHARMACEUTICALS LIMITED (GB) 1992-10-21 — — EP disclosed
WO-1992007869-A1 INHIBITORS AND SUBSTRATES OF THROMBIN THROMBOSIS RESEARCH INSTITUTE (GB) 1992-05-14 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120202821-A1 CONFORMATIONALLY CONSTRAINED, FULLY SYNTHETIC MACROCYCLIC COMPOUNDS HTR2B, MC1R, HTR1A ALDH1A1 4268/4885LMNA 2246/4885MAPT 3584/4885
US-20180201647-A1 Peptoid ARG1, ARGLU1, QPCT ALDH1A1 4876/4885LMNA 3209/4885MAPT 1735/4885
US-20260098061-A1 EPHA2-BINDING PENDING PEPTIDE AND COMPOSITION COMPRISING SAME EPHA2, EPHA1, EPHB1 ALDH1A1 4034/4885LMNA 2840/4885MAPT 3291/4885
US-10017481-B2 Conformationally constrained, fully synthetic macrocyclic compounds CTSE, CTSB, CTSS ALDH1A1 4415/4885LMNA 2799/4885MAPT 4679/4885
US-20120270881-A1 CONFORMATIONALLY CONSTRAINED, FULLY SYNTHETIC MACROCYCLIC COMPOUNDS KCNB1, KCNAB1, KCNMB1 ALDH1A1 4142/4885LMNA 2161/4885MAPT 3859/4885
US-20150051183-A1 CONFORMATIONALLY CONSTRAINED, FULLY SYNTHETIC MACROCYCLIC COMPOUNDS CTSE, CTSB, CTSS ALDH1A1 4415/4885LMNA 2799/4885MAPT 4679/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.