SCHEMBL13835929

SCHEMBL13835929

C1CCCN2CCC2CC1

nearest known ligand 0.72

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
L3MBTL3 Q96JM7 6/20 0.50
L3MBTL1 Q9Y468 5/20 0.50
CYP2D6 P10635 1/20 0.50
CYP2C19 P33261 1/20 0.50
HTR6 P50406 1/20 0.50
SLC18A3 Q16572 1/20 0.48
OPRM1 P35372 1/20 0.47
OPRL1 P41146 1/20 0.47
MBTD1 Q05BQ5 4/20 0.45
PHGDH O43175 1/20 0.45
MGLL Q99685 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22048336 1.00 L3MBTL3 (0.50) L3MBTL3L3MBTL1CYP2D6CYP2C19HTR6
SCHEMBL13835639 1.00
SCHEMBL24511688 0.97 L3MBTL3 (0.52) L3MBTL3L3MBTL1CYP2D6CYP2C19HTR6
SCHEMBL15321 0.97
SCHEMBL18946139 0.97 L3MBTL3 (0.52) L3MBTL3L3MBTL1CYP2D6CYP2C19HTR6
SCHEMBL21057351 0.94 HTR6 (0.54) L3MBTL3L3MBTL1CYP2D6CYP2C19HTR6
SCHEMBL21422636 0.94 HTR6 (0.54) L3MBTL3L3MBTL1CYP2D6CYP2C19HTR6
SCHEMBL22216666 0.94 HTR6 (0.54) L3MBTL3L3MBTL1CYP2D6CYP2C19HTR6
SCHEMBL60131 0.94 HTR6 (0.54) L3MBTL3L3MBTL1CYP2D6CYP2C19HTR6
SCHEMBL1828721 0.94 HTR6 (0.54) L3MBTL3L3MBTL1CYP2D6CYP2C19HTR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3281933-B1 (METH)ACRYLATE MANUFACTURING METHOD TOAGOSEI CO LTD (JP) 2020-08-19 EP disclosed
US-10619058-B2 Curable composition TOAGOSEI CO., LTD. (JP) 2020-04-14 US disclosed
US-10611856-B2 Curable composition TOAGOSEI CO., LTD. (JP) 2020-04-07 US disclosed
EP-3133058-B1 MULTIFUNCTIONAL (METH)ACRYLATE MANUFACTURING METHOD TOAGOSEI CO LTD (JP) 2019-05-29 EP disclosed
US-10266476-B2 (Meth)acrylate manufacturing method TOAGOSEI CO., LTD. (JP) 2019-04-23 US disclosed
US-10065916-B2 Method for producing (meth)acrylate TOAGOSEI CO., LTD (JP) 2018-09-04 US disclosed
US-20180237629-A1 CURABLE COMPOSITION TOAGOSEI CO., LTD. (JP) 2018-08-23 US disclosed
US-10035752-B2 Multifunctional (meth)acrylate manufacturing method TOAGOSEI CO., LTD. (JP) 2018-07-31 US disclosed
US-20180187026-A1 CURABLE COMPOSITION TOAGOSEI CO., LTD. (JP) 2018-07-05 US disclosed
US-20180171038-A1 CURABLE COMPOSITION TOAGOSEI CO., LTD. (JP) 2018-06-21 US disclosed
US-20180105483-A1 METHOD FOR PRODUCING (METH)ACRYLATE TOAGOSEI CO., LTD. (JP) 2018-04-19 US disclosed
EP-3281933-A1 (METH)ACRYLATE MANUFACTURING METHOD Toagosei Co., Ltd. (JP) 2018-02-14 EP disclosed
EP-3269700-A1 METHOD FOR PRODUCING (METH)ACRYLATE Toagosei Co., Ltd. (JP) 2018-01-17 EP disclosed
US-20170204044-A1 MULTIFUNCTIONAL (METH)ACRYLATE MANUFACTURING METHOD TOAGOSEI CO., LTD. (JP) 2017-07-20 US disclosed
EP-3133058-A1 MULTIFUNCTIONAL (METH)ACRYLATE MANUFACTURING METHOD Toagosei Co., Ltd. (JP) 2017-02-22 EP disclosed
US-20160326157-A1 MONOBACTAMS AND METHODS OF THEIR SYNTHESIS AND USE PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2016-11-10 US disclosed
WO-2015103583-A1 MONOBACTAMS AND METHODS OF THEIR SYNTHESIS AND USE PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2015-07-09 WO disclosed
US-8506913-B2 Acidic gas absorbent, acidic gas removal device, and acidic gas removal method KABUSHIKI KAISHA TOSHIBA (JP) 2013-08-13 US disclosed
EP-2554243-A1 ACIDIC GAS ABSORBENT, ACIDIC GAS REMOVAL DEVICE, AND ACIDIC GAS REMOVAL METHOD Kabushiki Kaisha Toshiba (JP) 2013-02-06 EP disclosed
US-20120294785-A1 ACIDIC GAS ABSORBENT, ACIDIC GAS REMOVAL DEVICE, AND ACIDIC GAS REMOVAL METHOD KABUSHIKI KAISHA TOSHIBA (JP) 2012-11-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160326157-A1 MONOBACTAMS AND METHODS OF THEIR SYNTHESIS AND USE MGAM, BPGM, MRPL21 L3MBTL3 3592/4885L3MBTL1 2869/4885CYP2D6 57/4885
US-10065916-B2 Method for producing (meth)acrylate MMAB, ADH5, ADH1A L3MBTL3 3046/4885L3MBTL1 3412/4885CYP2D6 957/4885
US-20180171038-A1 CURABLE COMPOSITION KAT2B, ACR, GK L3MBTL3 3584/4885L3MBTL1 3527/4885CYP2D6 4795/4885
US-20180187026-A1 CURABLE COMPOSITION AZI2, KAT2A, KAT2B L3MBTL3 3167/4885L3MBTL1 3066/4885CYP2D6 4844/4885
US-10035752-B2 Multifunctional (meth)acrylate manufacturing method MMAB, AMD1, ADH5 L3MBTL3 1752/4885L3MBTL1 1501/4885CYP2D6 1416/4885
US-10611856-B2 Curable composition ACR, KAT2B, KAT5 L3MBTL3 3480/4885L3MBTL1 3189/4885CYP2D6 4824/4885
US-20170204044-A1 MULTIFUNCTIONAL (METH)ACRYLATE MANUFACTURING METHOD MMAB, AMD1, ADH5 L3MBTL3 1752/4885L3MBTL1 1501/4885CYP2D6 1416/4885
US-20180105483-A1 METHOD FOR PRODUCING (METH)ACRYLATE MMAB, ADH5, ADH1A L3MBTL3 3046/4885L3MBTL1 3412/4885CYP2D6 957/4885
US-10266476-B2 (Meth)acrylate manufacturing method MMAB, PAM, MAT2B L3MBTL3 3148/4885L3MBTL1 3978/4885CYP2D6 2408/4885
US-10619058-B2 Curable composition ZMYND8, AZI2, KAT2A L3MBTL3 2648/4885L3MBTL1 2368/4885CYP2D6 4854/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.