Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 known ✓ | O43570 | 6/20 | 0.48 |
| ▸ | CA1 known ✓ | P00915 | 6/20 | 0.48 |
| ▸ | CA2 known ✓ | P00918 | 6/20 | 0.48 |
| ▸ | THRB known ✓ | P10828 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 6/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | NOS3 | P29474 | 1/20 | 0.37 |
| ▸ | NOS1 | P29475 | 1/20 | 0.37 |
| ▸ | NOS2 | P35228 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11605944 | 1.00 | CA12 (0.48) | CA12CA1CA2CA9THRB | |
| SCHEMBL20142451 | 1.00 | CA12 (0.48) | CA12CA1CA2CA9THRB | |
| SCHEMBL35267 | 1.00 | CA12 (0.48) | CA12CA1CA2CA9THRB | |
| Potassium Ion SCHEMBL9788101 | 0.95 | CA12 (0.47) | CA12CA1CA2CA9THRB | |
| SCHEMBL11043254 | 0.95 | CA12 (0.43) | CA12CA1CA2CA9THRB | |
| SCHEMBL11039650 | 0.95 | CA12 (0.43) | CA12CA1CA2CA9THRB | |
| Potassium Ion SCHEMBL9851169 | 0.95 | CA12 (0.47) | CA12CA1CA2CA9THRB | |
| SCHEMBL10397109 | 0.91 | — | — | |
| Zinc Ion SCHEMBL5450533 | 0.86 | NOS3 (0.44) | CA12CA1CA2CA9POLB | |
| Potassium Ion SCHEMBL11855148 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108017775-B | Preparation method of polyurethane RAFT reagent | 上饶师范学院 | 2022-06-21 | — | — | CN | claimed |
| CN-119708391-A | Antioxidant block copolymer emulsifier nanoparticle and synthesis method thereof | 常州大学 | 2025-03-28 | — | — | CN | disclosed |
| US-11459420-B2 | Block copolymers, membranes and methods | The Florida State University Research Foundation, Inc. (US) | 2022-10-04 | — | — | US | disclosed |
| CN-108017775-B | Preparation method of polyurethane RAFT reagent | 上饶师范学院 | 2022-06-21 | — | — | CN | disclosed |
| CN-108017775-B | Preparation method of polyurethane RAFT reagent | 上饶师范学院 | 2022-06-21 | — | — | CN | disclosed |
| US-20210332177-A1 | Block Copolymers, Membranes and Methods | The Florida State University Research Foundation, Inc. | 2021-10-28 | — | — | US | disclosed |
| EP-2746308-B1 | USE OF BLOCK COPOLYMER AND ANTITHROMBOTIC COATING AGENT | DAINIPPON INK & CHEMICALS (JP) | 2016-11-30 | — | — | EP | disclosed |
| US-9474835-B2 | Block copolymer and antithrombotic coating agent | KAWAMURA INSTITUTE OF CHEMICAL RESEARCH (JP) | 2016-10-25 | — | — | US | disclosed |
| EP-2707404-B1 | BLOCK POLYMER INCLUDING ISOBUTYL ACRYLATE AND ACRYLIC ACID, COSMETIC COMPOSITION AND TREATMENT METHOD | OREAL (FR) | 2015-09-30 | — | — | EP | disclosed |
| US-20140235748-A1 | BLOCK COPOLYMER AND ANTITHROMBOTIC COATING AGENT | DIC CORPORATION (JP) | 2014-08-21 | — | — | US | disclosed |
| EP-2746308-A2 | BLOCK COPOLYMER, AND ANTITHROMBOTIC COATING AGENT | Kawamura Institute Of Chemical Research (JP) | 2014-06-25 | — | — | EP | disclosed |
| EP-2707404-A1 | BLOCK POLYMER INCLUDING ISOBUTYL ACRYLATE AND ACRYLIC ACID, COSMETIC COMPOSITION AND TREATMENT METHOD | L'OREAL (FR) | 2014-03-19 | — | — | EP | disclosed |
| WO-2012156630-A1 | BLOCK POLYMER INCLUDING ISOBUTYL ACRYLATE AND ACRYLIC ACID, COSMETIC COMPOSITION AND TREATMENT METHOD | L'OREAL (FR) | 2012-11-22 | — | — | WO | disclosed |