Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 12/20 | 0.47 |
| ▸ | MMP13 | P45452 | 12/20 | 0.47 |
| ▸ | MMP1 | P03956 | 9/20 | 0.46 |
| ▸ | MMP3 | P08254 | 7/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 4/20 | 0.43 |
| ▸ | MMP14 | P50281 | 3/20 | 0.43 |
| ▸ | MMP8 | P22894 | 2/20 | 0.43 |
| ▸ | MMP16 | P51512 | 1/20 | 0.42 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.42 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.41 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.41 |
| ▸ | BMP1 | P13497 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13899011 | 0.87 | LMNA (0.47) | MMP2MMP13MMP1MMP3MMP9 | |
| SCHEMBL3921655 | 0.84 | MMP2 (0.47) | MMP2MMP13MMP1MMP3MMP9 | |
| SCHEMBL13899009 | 0.82 | MMP13 (0.52) | MMP2MMP13MMP1MMP3MMP9 | |
| SCHEMBL13898736 | 0.81 | BMP1 (0.48) | MMP2MMP13MMP1MMP3MMP9 | |
| SCHEMBL13899003 | 0.78 | MMP3 (0.74) | MMP2MMP13MMP1MMP3MMP9 | |
| SCHEMBL3914725 | 0.75 | MMP2 (0.67) | MMP2MMP13MMP1MMP3MMP9 | |
| SCHEMBL3914722 | 0.75 | MMP2 (0.67) | MMP2MMP13MMP1MMP3MMP9 | |
| SCHEMBL231737 | 0.74 | MMP1 (0.55) | MMP2MMP13MMP1MMP3MMP9 | |
| SCHEMBL6817940 | 0.74 | MMP1 (0.48) | MMP2MMP13MMP1MMP3MMP9 | |
| SCHEMBL3914343 | 0.72 | MMP1 (0.60) | RORCMMP2MMP13MMP1MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7504537-B2 | Hydroxamic acid derivative and MMP inhibitor containing the same as active ingredient | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2009-03-17 | — | — | US | disclosed |
| US-7504537-B2 | Hydroxamic acid derivative and MMP inhibitor containing the same as active ingredient | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2009-03-17 | — | — | US | disclosed |