Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 1/20 | 0.37 |
| ▸ | GABRD | O14764 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.37 |
| ▸ | GABRE | P78334 | 1/20 | 0.37 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.37 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.37 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.37 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10268052 | 0.87 | MEN1 (0.40) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL10198831 | 0.87 | GABRP (0.44) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL15942789 | 0.79 | CYP3A4 (0.35) | MMP13MEN1CYP3A4PTGS1DRD3 | |
| SCHEMBL15692569 | 0.79 | KMO (0.46) | MMP13 | |
| SCHEMBL30307658 | 0.76 | MEN1 (0.35) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL28955966 | 0.76 | MEN1 (0.35) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL13976876 | 0.71 | KDM4E (0.35) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL24242591 | 0.67 | PPARA (0.42) | MEN1CYP3A4PTGS1DRD3KMT2A | |
| SCHEMBL20953597 | 0.67 | PPARA (0.42) | MEN1CYP3A4PTGS1DRD3KMT2A | |
| SCHEMBL26719914 | 0.67 | ACHE (0.39) | PTGS1FYNHSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120295922-A1 | Compounds For Use In Treatment Of Mucositis | POLYMEDIX, INC. (US) | 2012-11-22 | — | — | US | disclosed |
| US-20120295871-A1 | HEPARIN-BASED COMPOSITIONS AND METHODS FOR THE INHIBITION OF METASTASIS | DIAMOND, PAUL | 2012-11-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120295922-A1 | Compounds For Use In Treatment Of Mucositis | MUC1, FUT6, MMP8 | GABRP 3692/4885GABRD 2564/4885GABRA1 4070/4885 |
| US-20120295871-A1 | HEPARIN-BASED COMPOSITIONS AND METHODS FOR THE INHIBITION OF METASTASIS | HPSE, SERPINC1, CD44 | GABRP 3611/4885GABRD 4730/4885GABRA1 4614/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.