Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.37 |
| ▸ | DHFR | P00374 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.30 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.30 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL727390 | 0.85 | ELANE (0.35) | DHFRELANE | |
| SCHEMBL727589 | 0.72 | ALDH1A1 (0.44) | — | |
| SCHEMBL2968661 | 0.69 | ELANE (0.33) | ELANE | |
| SCHEMBL2970690 | 0.69 | ALDH1A1 (0.39) | DHFRELANE | |
| SCHEMBL25765765 | 0.67 | DHFR (0.44) | TAAR1DHFR | |
| SCHEMBL2552345 | 0.67 | ADRB2 (0.35) | — | |
| SCHEMBL9861529 | 0.66 | SHBG (0.34) | DHFR | |
| SCHEMBL24152560 | 0.65 | TAAR1 (0.36) | TAAR1DHFR | |
| SCHEMBL728561 | 0.65 | ALDH1A1 (0.34) | ELANE | |
| SCHEMBL26644683 | 0.65 | SHBG (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080315155-A1 | Diamines Having Reduced Color | ALBEMARLE CORPORATION (US) | 2008-12-25 | — | — | US | disclosed |
| US-20080262187-A1 | Blends of Diamines Having Reduced Color | ALBEMARLE CORPORATION (US) | 2008-10-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080262187-A1 | Blends of Diamines Having Reduced Color | DDT, DDC, AOC1 | TAAR1 896/4885DHFR 305/4885ELANE 3801/4885 |
| US-20080315155-A1 | Diamines Having Reduced Color | DDT, DPYD, DDC | TAAR1 748/4885DHFR 115/4885ELANE 3624/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.