Sugi Predict

Sugi Predict / Compounds / SCHEMBL14010381

SCHEMBL14010381

SCHEMBL14010381

Cc1ccc([Co](=O)c2ccccc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ACHE P22303 2/20 0.48
▸ LMNA P02545 2/20 0.48
▸ TSHR P16473 1/20 0.48
▸ ALOX12 P18054 1/20 0.48
▸ CES2 O00748 1/20 0.43
▸ CES1 P23141 1/20 0.43
▸ HPGD P15428 3/20 0.41
▸ TDP1 Q9NUW8 2/20 0.40
▸ SMN1; SMN2 Q16637 6/20 0.39
▸ NPC1 O15118 5/20 0.39
▸ RAB9A P51151 5/20 0.39
▸ HTT P42858 2/20 0.39
▸ MEN1 O00255 2/20 0.39
▸ KMT2A Q03164 2/20 0.39
▸ CA12 O43570 3/20 0.37
▸ CA9 Q16790 3/20 0.37
▸ CYP1A2 P05177 1/20 0.37
▸ CYP3A4 P08684 1/20 0.37
▸ ATM Q13315 1/20 0.37
▸ L3MBTL1 Q9Y468 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12799090 0.89 ACHE (0.50) ACHELMNATSHRALOX12CES2
SCHEMBL14182279 0.84 ALDH1A1 (0.35) ACHELMNATSHRALOX12CES2
SCHEMBL12799091 0.82 HPGD (0.43) ACHELMNACES2CES1HPGD
SCHEMBL12230610 0.73 MAPT (0.57) LMNACES2CES1HPGDSMN1; SMN2
P-Xylene SCHEMBL887790 0.71 ACHE (0.92) ACHELMNATSHRALOX12CES2
P-Xylene SCHEMBL11504018 0.71 ACHE (0.92) ACHELMNATSHRALOX12CES2
P-Xylene SCHEMBL17318276 0.71 ACHE (0.92) ACHELMNATSHRALOX12CES2
P-Xylene SCHEMBL9126485 0.71 ACHE (0.92) ACHELMNATSHRALOX12CES2
P-Xylene SCHEMBL3468304 0.71 ACHE (0.80) ACHELMNATSHRALOX12CES2
P-Xylene SCHEMBL9150238 0.71 ACHE (0.80) ACHELMNATSHRALOX12CES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 577 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024133996-A1 METHOD FOR PREPARING TRANSPARENT AND HEAT-SENSITIVE POLYCAPROLACTAM COATINGS ON POLYMER SUBSTRATES CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (ES) 2024-06-27 — — WO disclosed
US-11913944-B2 Photoaffinity probes PROMEGA CORPORATION (US) 2024-02-27 — — US disclosed
US-11913944-B2 Photoaffinity probes PROMEGA CORPORATION (US) 2024-02-27 — — US disclosed
US-20240025873-A1 METHOD FOR PRODUCING KETONE DERIVATIVE TOKUYAMA CORPORATION (JP) 2024-01-25 — — US disclosed
US-20240025873-A1 METHOD FOR PRODUCING KETONE DERIVATIVE TOKUYAMA CORPORATION (JP) 2024-01-25 — — US disclosed
WO-2024018040-A1 CURABLE COMPOSITIONS ARKEMA FRANCE (FR) 2024-01-25 — — WO disclosed
WO-2024018041-A1 OLIGOMERS COMPRISING POLYMERIZED HIGH-TG MONOMERS ARKEMA FRANCE (FR) 2024-01-25 — — WO disclosed
EP-4310117-A1 CURABLE COMPOSITIONS ARKEMA FRANCE (FR) 2024-01-24 — — EP disclosed
EP-4310115-A1 OLIGOMERS COMPRISING POLYMERIZED HIGH-TG MONOMERS ARKEMA FRANCE (FR) 2024-01-24 — — EP disclosed
US-11807623-B2 Nucleic acid-binding photoprobes and uses thereof ARRAKIS THERAPEUTICS, INC. (US) 2023-11-07 — — US disclosed
US-7183278-B1 Picolinamide derivative and harmful organism control agent comprising said picolinamide derivative as active component MEIJI SEIKA KAISHA, LTD. (JP) 2007-02-27 — — US disclosed
US-7176297-B2 Photoactivatable silane compounds and methods for their synthesis and use AFFYMETRIX, INC. (US) 2007-02-13 — — US disclosed
US-7176297-B2 Photoactivatable silane compounds and methods for their synthesis and use AFFYMETRIX, INC. (US) 2007-02-13 — — US disclosed
US-7166603-B2 Dihydropyrimidone inhibitors of calcium channel function BRISTOL-MYERS SQUIBB CO. (US) 2007-01-23 — — US disclosed
US-7157486-B2 Viral polymerase inhibitors BOEHRINGER INGELHEIM (CANADA) LTD. (CA) 2007-01-02 — — US disclosed
EP-1659115-A1 Synthesis of substituted 2H-indazole derivatives as anti-angiogenic agents Yung Shin Pharm. Ind. Co., Ltd. (TW) 2006-05-24 — — EP disclosed
US-20060106032-A1 Synthesis of N2 - (substituted arylmethyl) -3- (substituted phenyl) indazoles as novel anti-angiogenic agents YUNG SHIN PHARM. IND. CO., LTD. (TW) 2006-05-18 — — US disclosed
US-20060019900-A1 Alpha-4 beta-1 integrin ligands for imaging and therapy THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2006-01-26 — — US disclosed
WO-2003034989-A2 α-HYDROXYARYLBUTANAMINE INHIBITORS OF ASPARTYL PROTEASE ENANTA PHARMACEUTICALS, INC. (US) 2003-05-01 — — WO disclosed
WO-2003007954-A2 SULFONYL ARYL HYDROXAMATES AND THEIR USE AS MATRIX METALLOPROTEASE INHIBITORS PHARMACIA CORPORATION (US) 2003-01-30 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060019900-A1 Alpha-4 beta-1 integrin ligands for imaging and therapy ITGA4, ITGB4, ITGA1 ACHE 4118/4885LMNA 2391/4885TSHR 1254/4885
US-20060106032-A1 Synthesis of N2 - (substituted arylmethyl) -3- (substituted phenyl) indazoles as novel anti-angiogenic agents FLT4, FLT1, KDR ACHE 4667/4885LMNA 3368/4885TSHR 4054/4885
US-20240025873-A1 METHOD FOR PRODUCING KETONE DERIVATIVE HSD17B7, BCKDK, KARS1 ACHE 2928/4885LMNA 3073/4885TSHR 1912/4885
US-11807623-B2 Nucleic acid-binding photoprobes and uses thereof NSUN3, NSUN2, TARBP1 ACHE 4779/4885LMNA 1870/4885TSHR 1752/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.