Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 1/20 | 0.43 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.43 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.41 |
| ▸ | SCD5 | Q86SK9 | 2/20 | 0.36 |
| ▸ | SCD | O00767 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5090995 | 0.87 | HSD17B1 (0.46) | HSD17B1HSD17B2SCD5SCDMGLL | |
| SCHEMBL4514314 | 0.76 | HSD17B1 (0.47) | HSD17B1HSD17B2MGLLKDM1ADRD2 | |
| SCHEMBL4507868 | 0.71 | SLC6A2 (0.44) | HSD17B1HSD17B2KDM4EALDH1A1HSD17B10 | |
| SCHEMBL5091095 | 0.70 | PGR (0.38) | KDM1ACHRM2CHRM1CHRM3CYP2C19 | |
| SCHEMBL4519627 | 0.70 | GPR119 (0.47) | HSD17B1HSD17B2IRAK4CHRM2CHRM1 | |
| SCHEMBL5097362 | 0.69 | GPR119 (0.44) | IRAK4ALDH1A1 | |
| SCHEMBL5103709 | 0.67 | GPR142 (0.40) | SCD5ALDH1A1 | |
| SCHEMBL3658864 | 0.67 | CHRM2 (0.44) | CHRM2CHRM1CHRM3LMNACYP2C9 | |
| SCHEMBL5094870 | 0.66 | SIGMAR1 (0.39) | KDM4ECYP1A2CYP2D6CYP2C19DRD2 | |
| SCHEMBL5090969 | 0.66 | SLC9A1 (0.38) | KDM1ACHRM2CHRM1CHRM3CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080306111-A1 | TRICYCLIC DELTA- OPIOID MODULATORS | CARSON JOHN R | 2008-12-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080306111-A1 | TRICYCLIC DELTA- OPIOID MODULATORS | OPRD1, OPRK1, OPRL1 | HSD17B1 769/4885HSD17B2 920/4885IRAK4 2333/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.