Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.50 |
| ▸ | RAF1 | P04049 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4812903 | 0.81 | KDM4E (0.47) | LMNAALDH1A1MAPK1HPGDSMN1; SMN2 | |
| SCHEMBL13753629 | 0.80 | VCAM1 (0.57) | LMNAALDH1A1MAPTHPGDVCAM1 | |
| SCHEMBL14110006 | 0.80 | ALDH1A1 (0.47) | LMNAALDH1A1MAPTMAPK1HPGD | |
| SCHEMBL1811403 | 0.78 | DGAT2 (0.47) | ALDH1A1MAPT | |
| SCHEMBL19075733 | 0.78 | TTR (0.48) | LMNAALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL6866237 | 0.76 | VCAM1 (0.62) | LMNAALDH1A1MAPTMAPK1HPGD | |
| SCHEMBL1812523 | 0.74 | DGAT2 (0.44) | MAPTSMN1; SMN2PKM | |
| SCHEMBL51755 | 0.74 | LMNA (0.72) | LMNAALDH1A1MAPTMAPK1HPGD | |
| SCHEMBL7973732 | 0.74 | VCAM1 (0.68) | LMNAALDH1A1MAPTMAPK1HPGD | |
| SCHEMBL16710209 | 0.73 | L3MBTL1 (0.57) | LMNAALDH1A1MAPTHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7408076-B2 | 2-Bromoanaline and 2-chloroaniline compounds | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-08-05 | — | — | US | disclosed |