SCHEMBL14240406

SCHEMBL14240406

Cc1cccc2c1sc1c(-n3c4ccccc4c4ccccc43)cccc12

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALKBH5 Q6P6C2 1/20 0.42
▸ FTO Q9C0B1 1/20 0.42
▸ ALDH1A1 P00352 4/20 0.40
▸ L3MBTL1 Q9Y468 2/20 0.37
▸ KDM4E B2RXH2 1/20 0.37
▸ ATM Q13315 1/20 0.37
▸ PARP15 Q460N3 1/20 0.36
▸ PARP10 Q53GL7 1/20 0.36
▸ TNKS2 Q9H2K2 1/20 0.36
▸ PARP2 Q9UGN5 1/20 0.36
▸ TSHR P16473 1/20 0.36
▸ GPR3 P46089 1/20 0.35
▸ CYP2A6 P11509 2/20 0.34
▸ CYP1A2 P05177 1/20 0.34
▸ POLB P06746 1/20 0.34
▸ SMN1; SMN2 Q16637 1/20 0.34
▸ RAB9A P51151 1/20 0.33
▸ LMNA P02545 3/20 0.33
▸ MAPT P10636 2/20 0.33
▸ HTT P42858 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL126274 0.89 ALDH1A1 (0.47) ALKBH5FTOALDH1A1L3MBTL1KDM4E
SCHEMBL10092208 0.81 ALDH1A1 (0.41) ALDH1A1L3MBTL1KDM4EATMGPR3
SCHEMBL15926248 0.81 TSPO (0.39) ALDH1A1
SCHEMBL19660505 0.80 ALDH1A1 (0.40) ALDH1A1L3MBTL1KDM4EATMGPR3
SCHEMBL12925600 0.80 ALDH1A1 (0.40) ALDH1A1L3MBTL1KDM4EATMGPR3
SCHEMBL17792926 0.80 ALDH1A1 (0.41) ALDH1A1L3MBTL1KDM4EATMGPR3
SCHEMBL15959784 0.80 ALDH1A1 (0.37) ALDH1A1L3MBTL1KDM4EATMTSHR
SCHEMBL19068363 0.80 ALDH1A1 (0.37) ALDH1A1L3MBTL1KDM4EATMTSHR
SCHEMBL2548411 0.79 GPR3 (0.45) ALDH1A1L3MBTL1KDM4EATMTNKS2
SCHEMBL18381843 0.78 GPR3 (0.43) ALDH1A1L3MBTL1KDM4EATMTNKS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230131934-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-04-27 — — US disclosed
US-20230131934-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-04-27 — — US disclosed
EP-3632921-A1 ANCILLARY LIGANDS FOR ORGANOMETALLIC COMPLEXES Universal Display Corporation (US) 2020-04-08 — — EP disclosed
US-10403825-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2019-09-03 — — US disclosed
US-9698357-B2 Phenanthroline-based compound and use thereof LUMINESCENCE TECHNOLOGY CORP. (TW) 2017-07-04 — — US disclosed
US-20170077410-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND USE THEREOF LUMINESCENCE TECHNOLOGY CORP. (TW) 2017-03-16 — — US disclosed
US-20160372679-A1 COMPOUNDS FOR ORGANIC ELECTROLUMINESCENCE DEVICE LUMINESCENCE TECHNOLOGY CORP. (TW) 2016-12-22 — — US disclosed
US-20160211456-A1 PHENANTHRO[9,10-b]TETRAPHENYLENE DERIVATIVE AND USE THEREOF LUMINESCENCE TECHNOLOGY CORP. 2016-07-21 — — US disclosed
US-20160204345-A1 DITRIPHENYLENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME LUMINESCENCE TECHNOLOGY CORP. (TW) 2016-07-14 — — US disclosed
US-20160155949-A1 PHENANTHROLINE-BSAED COMPOUND AND USE THEREOF LUMINESCENCE TECHNOLOGY CORP. 2016-06-02 — — US disclosed
US-9190619-B2 Compound for organic electroluminescence device LUMINESCENCE TECHNOLOGY CORP (TW) 2015-11-17 — — US disclosed
US-9166177-B2 Ditriphenylene derivative and organic electroluminescent device using the same LUMINESCENCE TECHNOLOGY CORP. (TW) 2015-10-20 — — US disclosed
US-20150243903-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2015-08-27 — — US disclosed
US-20150243903-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2015-08-27 — — US disclosed
US-20150214492-A1 COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE LUMINESCENCE TECHNOLOGY CORP (TW) 2015-07-30 — — US disclosed
US-20140231754-A1 DITRIPHENYLENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME Yen, Feng-wen (TW) 2014-08-21 — — US disclosed
WO-2012170463-A1 HETEROLEPTIC IRIDIUM CARBENE COMPLEXES AND LIGHT EMITTING DEVICE USING THEM UNIVERSAL DISPLAY CORPORATION (US) 2012-12-13 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10403825-B2 Organic electroluminescent materials and devices OCIAD1, OCIAD2, OSBP ALKBH5 807/4885FTO 300/4885ALDH1A1 2138/4885
US-20150243903-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, OSBP ALKBH5 807/4885FTO 300/4885ALDH1A1 2138/4885
US-20160372679-A1 COMPOUNDS FOR ORGANIC ELECTROLUMINESCENCE DEVICE CCNE2, CYP3A4, CCNE1 ALKBH5 1420/4885FTO 1910/4885ALDH1A1 169/4885
US-20150214492-A1 COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE SLCO4C1, LEF1, SLCO2B1 ALKBH5 641/4885FTO 747/4885ALDH1A1 2542/4885
US-20230131934-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, OSBP ALKBH5 807/4885FTO 300/4885ALDH1A1 2138/4885
US-20160211456-A1 PHENANTHRO[9,10-b]TETRAPHENYLENE DERIVATIVE AND USE THEREOF POP1, TERB1, AP2B1 ALKBH5 1568/4885FTO 1509/4885ALDH1A1 2052/4885
US-20160204345-A1 DITRIPHENYLENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME NR2E1, NR0B1, NR2E3 ALKBH5 362/4885FTO 1412/4885ALDH1A1 3346/4885
US-20160155949-A1 PHENANTHROLINE-BSAED COMPOUND AND USE THEREOF MLX, BPNT1, PAH ALKBH5 2783/4885FTO 1963/4885ALDH1A1 3368/4885
US-20170077410-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND USE THEREOF HBS1L, EML4, EBPL ALKBH5 1126/4885FTO 451/4885ALDH1A1 2065/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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