SCHEMBL2548411

SCHEMBL2548411

c1ccc2c(c1)sc1c(-n3c4ccccc4c4ccccc43)cccc12

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 2/20 0.45
ALOX5 P09917 1/20 0.43
ALDH1A1 P00352 2/20 0.42
ATM Q13315 2/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
KDM4E B2RXH2 1/20 0.39
PARP14 Q460N5 1/20 0.37
TNKS O95271 1/20 0.36
TNKS2 Q9H2K2 1/20 0.36
MAPT P10636 4/20 0.36
RAB9A P51151 2/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
PRKDC P78527 2/20 0.34
HPGD P15428 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
TP53 P04637 1/20 0.33
ERCC5 P28715 1/20 0.33
FEN1 P39748 1/20 0.33
LIMK1 P53667 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18381843 0.98 GPR3 (0.43) GPR3ALOX5ALDH1A1ATML3MBTL1
SCHEMBL21671298 0.94 GPR3 (0.39) GPR3ALOX5ALDH1A1ATML3MBTL1
SCHEMBL21671076 0.94 GPR3 (0.39) GPR3ALOX5ALDH1A1ATML3MBTL1
SCHEMBL15582935 0.94 ALOX5 (0.42) GPR3ALOX5ALDH1A1ATML3MBTL1
SCHEMBL25010826 0.92 ALOX5 (0.38) GPR3ALOX5ALDH1A1ATML3MBTL1
SCHEMBL18086149 0.92 ALOX5 (0.41) GPR3ALOX5ALDH1A1ATML3MBTL1
SCHEMBL18086148 0.92 GPR3 (0.41) GPR3ALOX5ALDH1A1ATML3MBTL1
SCHEMBL15128465 0.91 GPR3 (0.43) GPR3ALOX5ALDH1A1ATML3MBTL1
SCHEMBL18086142 0.90 GPR3 (0.39) GPR3ALOX5ALDH1A1ATML3MBTL1
SCHEMBL17246419 0.90 GPR3 (0.39) GPR3ALOX5ALDH1A1ATML3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11773320-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-10-03 US disclosed
US-11758807-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION 2023-09-12 US disclosed
EP-3447053-B1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORP (US) 2023-08-09 EP disclosed
US-20230144846-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-05-11 US disclosed
US-20230131934-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-04-27 US disclosed
EP-4060757-A1 HIGHLY EFFICIENT OLED DEVICES WITH VERY SHORT DECAY TIMES UDC Ireland Limited (IE) 2022-09-21 EP disclosed
EP-3330342-B1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DIODE USING SAME LT MATERIALS CO LTD (KR) 2021-09-15 EP disclosed
US-10381577-B2 Hetero-cyclic compound and organic light emitting device using the same HEESUNG MATERIAL LTD. (KR) 2019-08-13 US disclosed
US-10361378-B2 Organic electroluminescent device NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2019-07-23 US disclosed
US-9997726-B2 Dibenzothiophene-containing materials in phosphorescent light emitting diodes UNIVERSAL DISPLAY CORPORATION (US) 2018-06-12 US disclosed
WO-2011137072-A1 BICARBAZOLE CONTAINING COMPOUNDS FOR OLEDS UNIVERSAL DISPLAY CORPORATION (US) 2011-11-03 WO disclosed
WO-2011137072-A1 BICARBAZOLE CONTAINING COMPOUNDS FOR OLEDS UNIVERSAL DISPLAY CORPORATION (US) 2011-11-03 WO disclosed
US-20110260138-A1 BICARBZOLE CONTAINING COMPOUNDS FOR OLEDS UNIVERSAL DISPLAY CORPORATION (US) 2011-10-27 US disclosed
US-20110260138-A1 BICARBZOLE CONTAINING COMPOUNDS FOR OLEDS UNIVERSAL DISPLAY CORPORATION (US) 2011-10-27 US disclosed
US-20110260138-A1 BICARBZOLE CONTAINING COMPOUNDS FOR OLEDS UNIVERSAL DISPLAY CORPORATION (US) 2011-10-27 US disclosed
US-8007927-B2 Dibenzothiophene-containing materials in phosphorescent light emitting diodes UNIVERSAL DISPLAY CORPORATION (US) 2011-08-30 US disclosed
US-8007927-B2 Dibenzothiophene-containing materials in phosphorescent light emitting diodes UNIVERSAL DISPLAY CORPORATION (US) 2011-08-30 US disclosed
WO-2009085344-A2 DIBENZOTHIOPHENE-CONTAINING MATERIALS IN PHOSPHORESCENT LIGHT EMITTING DIODES UNIVERSAL DISPLAY CORPORATION (US) 2009-07-09 WO disclosed
US-20090167162-A1 DIBENZOTHIOPHENE-CONTAINING MATERIALS IN PHOSPHORESCENT LIGHT EMITTING DIODES UNIVERSAL DISPLAY CORPORATION (US) 2009-07-02 US disclosed
US-20090167162-A1 DIBENZOTHIOPHENE-CONTAINING MATERIALS IN PHOSPHORESCENT LIGHT EMITTING DIODES UNIVERSAL DISPLAY CORPORATION (US) 2009-07-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090167162-A1 DIBENZOTHIOPHENE-CONTAINING MATERIALS IN PHOSPHORESCENT LIGHT EMITTING DIODES DDT, BPNT1, DBF4 GPR3 4166/4885ALOX5 1131/4885ALDH1A1 877/4885
US-11773320-B2 Organic electroluminescent materials and devices CCNL2, HCN4, HNRNPL GPR3 817/4885ALOX5 4211/4885ALDH1A1 2869/4885
US-20230144846-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OXER1, OCIAD1, OCIAD2 GPR3 849/4885ALOX5 1708/4885ALDH1A1 501/4885
US-10381577-B2 Hetero-cyclic compound and organic light emitting device using the same CRY1, CRY2, PER2 GPR3 3743/4885ALOX5 1289/4885ALDH1A1 2238/4885
US-10361378-B2 Organic electroluminescent device ELF3, DDT, LEF1 GPR3 3910/4885ALOX5 1717/4885ALDH1A1 829/4885
US-20230131934-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, OSBP GPR3 1146/4885ALOX5 87/4885ALDH1A1 2138/4885
US-20110260138-A1 BICARBZOLE CONTAINING COMPOUNDS FOR OLEDS OCIAD1, OCIAD2, BRD7 GPR3 1107/4885ALOX5 169/4885ALDH1A1 471/4885
US-11758807-B2 Organic electroluminescent materials and devices GLRA3, ESRRG, GLRA1 GPR3 46/4885ALOX5 3996/4885ALDH1A1 2102/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.