Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.49 |
| ▸ | FEN1 | P39748 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | HRH2 | P25021 | 1/20 | 0.42 |
| ▸ | HTR1D | P28221 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1429352 | 1.00 | ALDH1A1 (0.51) | ALDH1A1ALOX5APFEN1TSHRLMNA | |
| SCHEMBL5151600 | 0.88 | UCHL1 (0.47) | ALDH1A1ALOX5APFEN1LMNANPSR1 | |
| SCHEMBL13574258 | 0.83 | LTA4H (0.44) | TSHR | |
| SCHEMBL6536147 | 0.82 | ALOX5AP (0.57) | ALDH1A1ALOX5APGPR119 | |
| SCHEMBL13316326 | 0.82 | ALOX5AP (0.49) | ALDH1A1ALOX5APFEN1LMNANPSR1 | |
| SCHEMBL2200111 | 0.82 | ALOX5AP (0.57) | ALDH1A1ALOX5APGPR119 | |
| SCHEMBL13166434 | 0.82 | ALOX5AP (0.49) | ALDH1A1ALOX5APFEN1LMNANPSR1 | |
| SCHEMBL6535662 | 0.82 | ALOX5AP (0.57) | ALDH1A1ALOX5APGPR119 | |
| SCHEMBL13316322 | 0.82 | ALOX5AP (0.49) | ALDH1A1ALOX5APFEN1LMNANPSR1 | |
| SCHEMBL6535343 | 0.82 | ALOX5AP (0.53) | ALDH1A1ALOX5APFEN1OPRK1GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2300454-B1 | Novel Microbiocides | SYNGENTA PARTICIPATIONS AG (CH) | 2015-01-21 | — | — | EP | disclosed |
| US-8623902-B2 | Microbiocides | SYNGENTA CROP PROTECTION, LLC (US) | 2014-01-07 | — | — | US | disclosed |
| US-20110207781-A1 | NOVEL MICROBIOCIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2011-08-25 | — | — | US | disclosed |
| EP-2300454-A1 | Novel Microbiocides | Syngenta Participations AG (CH) | 2011-03-30 | — | — | EP | disclosed |
| WO-2009153191-A1 | Novel Microbiocides | SYNGENTA PARTICIPATIONS AG (CH) | 2009-12-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110207781-A1 | NOVEL MICROBIOCIDES | CD14, FPR1, MPO | ALDH1A1 433/4885ALOX5AP 607/4885FEN1 1218/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.