Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.92 |
| ▸ | TP53 | P04637 | 1/20 | 0.92 |
| ▸ | SRD5A2 | P31213 | 4/20 | 0.75 |
| ▸ | CA1 | P00915 | 3/20 | 0.71 |
| ▸ | CA2 | P00918 | 3/20 | 0.71 |
| ▸ | CA12 | O43570 | 1/20 | 0.71 |
| ▸ | CA3 | P07451 | 1/20 | 0.71 |
| ▸ | TYR | P14679 | 1/20 | 0.71 |
| ▸ | DRD1 | P21728 | 1/20 | 0.71 |
| ▸ | CA4 | P22748 | 1/20 | 0.71 |
| ▸ | CA6 | P23280 | 1/20 | 0.71 |
| ▸ | CA5A | P35218 | 1/20 | 0.71 |
| ▸ | CA7 | P43166 | 1/20 | 0.71 |
| ▸ | CA9 | Q16790 | 1/20 | 0.71 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.71 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.71 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.69 |
| ▸ | DAO | P14920 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terephthalic Acid SCHEMBL28242783 | 0.96 | TSHR (0.86) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL175823 | 0.96 | TSHR (1.00) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL5053781 | 0.96 | TSHR (1.00) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL1655 | 0.96 | TSHR (1.00) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL2511919 | 0.96 | TSHR (1.00) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL10945724 | 0.93 | TSHR (0.80) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL25381766 | 0.92 | TSHR (0.92) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL1010632 | 0.92 | TSHR (0.92) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL10823257 | 0.92 | TSHR (0.92) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL20704876 | 0.92 | TSHR (0.92) | TSHRTP53SRD5A2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 351 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119838559-A | Preparation method of nano composite material for adsorbing potassium ions | 西安山海数联科技有限公司 | 2025-04-18 | — | — | CN | claimed |
| CN-119108521-A | Modified ternary positive electrode material and preparation method and application thereof | 格林美（无锡）能源材料有限公司 | 2024-12-10 | — | — | CN | claimed |
| CN-118867161-A | Al-Ti-C composite coated lithium cobalt oxide positive electrode material and preparation method and application thereof | 格林美（无锡）能源材料有限公司 | 2024-10-29 | — | — | CN | claimed |
| CN-118063859-A | Preparation method of high-dispersion nano silicon dioxide composite material | 扬州德鲁克科技有限公司 | 2024-05-24 | — | — | CN | claimed |
| CN-115724713-B | Method for preparing dipotassium terephthalate | 沈阳工业大学 | 2024-04-12 | — | — | CN | claimed |
| CN-116093328-B | Preparation method of high-magnification silicon-based negative electrode material, preparation method of carbon-free solid-state battery negative electrode piece and application | 哈尔滨工业大学 | 2023-09-22 | — | — | CN | claimed |
| CN-115404039-B | Polyurethane adhesive and preparation method and application thereof | 杭州之江有机硅化工有限公司 | 2023-06-16 | — | — | CN | claimed |
| CN-116093328-A | Preparation method of high-magnification silicon-based negative electrode material, preparation method of carbon-free solid-state battery negative electrode piece and application | 哈尔滨工业大学 | 2023-05-09 | — | — | CN | claimed |
| CN-115724713-A | Method for preparing dipotassium terephthalate | 沈阳工业大学 | 2023-03-03 | — | — | CN | claimed |
| US-11555797-B2 | Semiconductor-type battery-free gas sensor or humidity sensor including porous metal-organic framework and method of manufacturing the same | GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY | 2023-01-17 | — | — | US | claimed |
| US-20090263621-A1 | POROUS ORGANIC-INORGANIC HYBRID MATERIALS AND ADSORBENT COMPRISING THE SAME | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2009-10-22 | — | — | US | claimed |
| EP-2101912-A1 | A POROUS ORGANIC-INORGANIC HYBRID MATERIALS AND AN ABSORBENT COMPRISING THE SAME | Korea Research Institute of Chemical Technology (KR) | 2009-09-23 | — | — | EP | claimed |
| US-20090137707-A1 | Mixed salts of diorganylphosphinic acids and carboxylic acids | CLARIANT INTERNATIONAL LTD. | 2009-05-28 | — | — | US | claimed |
| WO-2008143385-A1 | PREPARATION OF SURFACE FUNCTIONALIZED POROUS ORGANIC-INORGANIC HYBRID MATERIALS OR MESOPOROUS MATERIALS WITH COORDINATIVELY UNSATURATED METAL SITES AND CATALYTIC APPLICATIONS THEREOF | KOREA RESERACH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2008-11-27 | — | — | WO | claimed |
| WO-2008072896-A1 | A POROUS ORGANIC-INORGANIC HYBRID MATERIALS AND AN ABSORBENT COMPRISING THE SAME | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2008-06-19 | — | — | WO | claimed |
| US-6764612-B2 | Encapsulated peroxide compositions | GEO SPECIALTY CHEMICALS, INC. | 2004-07-20 | — | — | US | claimed |
| US-6699403-B2 | ORGANIC PEROXIDE ENTRAINED IN PRECIPITATED METALLIC SOAP | GEO SPECIALTY CHEMICALS, INC. | 2004-03-02 | — | — | US | claimed |
| WO-2003082734-A1 | SUPPORTED PEROXIDE COMPOSITIONS | GEO SPECIALTY CHEMICALS, INC. (US) | 2003-10-09 | — | — | WO | claimed |
| US-20030178600-A1 | Encapsulated peroxide compositions | GEO SPECIALTY CHEMICALS, INC. | 2003-09-25 | — | — | US | claimed |
| US-20030178599-A1 | Supported peroxides | GEO SPECIALTY CHEMICALS, INC. | 2003-09-25 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090263621-A1 | POROUS ORGANIC-INORGANIC HYBRID MATERIALS AND ADSORBENT COMPRISING THE SAME | FTH1, SLC40A1, SLCO2A1 | TSHR 2510/4885TP53 1063/4885SRD5A2 1228/4885 |
| US-20090137707-A1 | Mixed salts of diorganylphosphinic acids and carboxylic acids | SLC10A6, SLC9A5, SLC9A3 | TSHR 1948/4885TP53 3343/4885SRD5A2 1346/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.