Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 5/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | TLR4 | O00206 | 1/20 | 0.47 |
| ▸ | TLR2 | O60603 | 1/20 | 0.47 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
| ▸ | BAX | Q07812 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | TGM2 | P21980 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9541963 | 0.82 | TRPA1 (0.57) | LTA4HTSHRALDH1A1LMNACA1 | |
| SCHEMBL1132385 | 0.80 | ALDH1A1 (0.39) | TSHRMAOAALDH1A1MEN1LMNA | |
| SCHEMBL9539397 | 0.77 | ALDH1A1 (0.41) | NPC1RAB9AALDH1A1LMNAL3MBTL1 | |
| SCHEMBL24193844 | 0.75 | ESR1 (0.50) | HPGDRAB9AALDH1A1AKR1B1MEN1 | |
| SCHEMBL9541503 | 0.75 | TSHR (0.42) | TSHRLMNAMMP2 | |
| SCHEMBL9541494 | 0.75 | NFE2L2 (0.52) | TSHRNPC1RAB9AALDH1A1MEN1 | |
| SCHEMBL14269409 | 0.75 | ALDH1A1 (0.42) | MAOAHPGDNPC1RAB9AALDH1A1 | |
| SCHEMBL9538596 | 0.75 | LMNA (0.42) | TSHRHPGDNPC1RAB9AALDH1A1 | |
| SCHEMBL20024694 | 0.73 | LTA4H (0.63) | LTA4HTSHRTLR4TLR2NR1H2 | |
| SCHEMBL3893562 | 0.72 | LTA4H (0.92) | LTA4HTSHRNR1H2BAXMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7253194-B2 | Compounds and inhibitors of phospholipases | THE UNIVERSITY OF QUEENSLAND (AU) | 2007-08-07 | — | — | US | disclosed |